Acoramidis

Acoramidis is used in adults to treat cardiomyopathy.

Acoramidis may also be used for purposes not listed in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Acoramidis is usually taken twice per day (about 12 hours apart) with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

Store this medicine in the original container at room temperature away from moisture and heat.

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

You should not take acoramidis if you are allergic to it.

It is not known if acoramidis will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using acoramidis.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Common side effects of acoramidis may include:

• stomach pain; or
• diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Usual Adult Dose for Hypertrophic Cardiomyopathy:

Recommended dosage: 712 mg orally twice dailyComments:-Can be administered with or without foodUse: For the treatment of the cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM) in adults to reduce cardiovascular death and cardiovascular-related hospitalization.

Usual Adult Dose for Amyloidogenic Transthyretin Amyloidosis:

Recommended dosage: 712 mg orally twice dailyComments:-Can be administered with or without foodUse: For the treatment of the cardiomyopathy of wild-type or variant transthyretin-mediated amyloidosis (ATTR-CM) in adults to reduce cardiovascular death and cardiovascular-related hospitalization.

Call your doctor for instructions if you miss a dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Other drugs may affect acoramidis, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.