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Amoxil
Generic name: amoxicillin
Brand names: Amoxil, Trimox (discontinued), Moxatag (discontinued)
What is Amoxil?
Amoxil is a penicillin antibiotic that fights bacteria.
Amoxil is used to treat many different types of infection caused by bacteria, such as tonsillitis, bronchitis, pneumonia, and infections of the ear, nose, throat, skin, or urinary tract.
Amoxil is also sometimes used together with another antibiotic called clarithromycin (Biaxin) to treat stomach ulcers caused by Helicobacter pylori infection. This combination is sometimes used with a stomach acid reducer called lansoprazole (Prevacid).
How should I take Amoxil?
Take Amoxil exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Take Amoxil at the same time each day.
Shake the oral suspension (liquid) before you measure a dose.
Measure liquid medicine with the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon). You may mix the liquid with water, milk, baby formula, fruit juice, or ginger ale. Drink all of the mixture right away. Do not save for later use.
You may need frequent medical tests.
If you are taking Amoxil with clarithromycin and/or lansoprazole to treat a stomach ulcer, use all of your medications as directed. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of an infection that is resistant to medication. Amoxil will not treat a viral infection such as the flu or a common cold.
Do not share this medicine with another person, even if they have the same symptoms you have.
This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using amoxicillin.
Store at room temperature away from moisture, heat, and light.
You may store liquid Amoxil in a refrigerator, but do not allow it to freeze. Throw away any liquid Amoxil that is not used within 14 days after it was mixed at the pharmacy.
Warnings
Do not use Amoxil if you are allergic to amoxicillin or to any other penicillin antibiotic, such as ampicillin (Omnipen, Principen), dicloxacillin (Dycill, Dynapen), oxacillin (Bactocill), penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids), and others.
Before using Amoxil, tell your doctor if you are allergic to cephalosporins such as Omnicef, Cefzil, Ceftin, Keflex, and others. Also tell your doctor if you have asthma, liver or kidney disease, a bleeding or blood clotting disorder, mononucleosis (also called "mono"), or any type of allergy.
Amoxicillin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking this medicine. Take this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Amoxicillin will not treat a viral infection such as the common cold or flu. Do not share this medication with another person, even if they have the same symptoms you have.
Antibiotic medicines can cause diarrhea. This may happen while you are taking Amoxil, or within a few months after you stop taking it. This may be a sign of a new infection. If you have diarrhea that is watery or bloody, stop taking Amoxil and call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
Before taking this medicine
You should not use Amoxil if you are allergic to any penicillin antibiotic, such as ampicillin, dicloxacillin, oxacillin, penicillin, or ticarcillin.
To make sure Amoxil is safe for you, tell your doctor if you have:
- kidney disease;
- mononucleosis (also called "mono");
- diarrhea caused by taking antibiotics;
- food or drug allergies (especially to a cephalosporin antibiotic such as Omnicef, Cefzil, Ceftin, Keflex, and others);
- phenylketonuria (PKU), if you are taking the chewable tablets.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Amoxicillin can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm, cervical cap, or contraceptive sponge) to prevent pregnancy.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risks.
Amoxil side effects
Get emergency medical help if you have signs of an allergic reaction to Amoxil (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Call your doctor at once if you have:
- severe stomach pain;
- symptoms of drug-induced enterocolitis syndrome (DIES), such as severe stomach pain and vomiting;
- diarrhea that is watery or bloody (even if it occurs months after your last dose); or
- confusion, agitation, anxiety, sleep problems, behavioral changes, dizziness, convulsions, or signs of aseptic meningitis.
Common Amoxil side effects may include:
- nausea, vomiting, diarrhea; or
- rash.
This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.
What other drugs will affect Amoxil?
Tell your doctor about all your other medicines, especially:
- any other antibiotics;
- allopurinol;
- probenecid; or
- a blood thinner - warfarin, Coumadin, Jantoven.
This list is not complete. Other drugs may interact with amoxicillin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Common questions about Amoxil
Amoxicillin rash: When should I be concerned?
What are the best antibiotics for a tooth infection?
Can you drink alcohol with amoxicillin?
Does amoxicillin expire? Is it safe to take after expiration?
What are the best antibiotics for pneumonia?
Is amoxicillin safe for dogs?
Does amoxicillin help with tooth infection and pain?
What is the Best Antibiotic for Strep Throat?
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Content is provided for education and is not medical advice. See our medical disclaimer. Source page medically reviewed by Philip Thornton, DipPharm on September 8, 2026.