Baxdrostat

Baxdrostat is used together with other blood pressure medicines in adults to treat hypertension (high blood pressure) that is not controlled by other medicines.

Baxdrostat may also be used for purposes not listed in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Baxdrostat is usually taken once per day. Follow your doctor's instructions.

You may take baxdrostat with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

You will need frequent blood tests before and during treatment with baxdrostat. Your treatment may be delayed, reduced, or permanently discontinued based on the results.

Do not stop taking baxdrostat unless your healthcare provider tells you to.

Store at room temperature away from moisture and heat.

Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Tell your doctor if you have or have ever had:

• high blood levels of potassium;
• low blood levels of sodium;
• diabetes; or
• kidney disease.

It is not known if baxdrostat will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask your doctor if it is safe to breastfeed while using baxdrostat.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Baxdrostat may cause serious side effects. Call your doctor at once if you have:

• high blood potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or
• low blood sodium--headache, confusion, problems with thinking or memory, feeling unsteady.

Common side effects of baxdrostat may include:

• high blood levels of potassium.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Usual Adult Dose for Hypertension:

2 mg orally once a dayUse: Treatment of hypertension in combination with other antihypertensive drugs to lower blood pressure in adults who are not adequately controlled on other agents.

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Do not take potassium supplements or use salt substitutes, unless your doctor has told you to.

Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

Tell your doctor about all your other medicines, especially drugs that can affect your blood potassium levels, such as potassium supplements or diuretics.

Other drugs may affect baxdrostat, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.