Bridion

Bridion is used in adults and children during surgery to reverse the effects of certain muscle-relaxing medicines, such as rocuronium and vecuronium.

Bridion helps restore muscle function that was blocked during surgery.

Bridion may also be used for purposes not listed in this medication guide.

Before you receive Bridion, tell your doctor about all your medical conditions or allergies, and all the medicines you are using. Also make sure your doctor knows if you are pregnant or breastfeeding.

Your medical caregivers will watch you closely for breathing problems, slow heartbeats, or signs of an allergic reaction after you receive Bridion.

You should not be treated with Bridion if you are allergic to it.

Tell your doctor if you have or have ever had:

• a bleeding or blood clotting disorder such as hemophilia;
• low levels of platelets in your blood;
• a breathing disorder;
• liver disease; or
• kidney disease (or if you are on dialysis).

It is not known whether Bridion will harm an unborn baby. Tell your doctor if you are pregnant.

Bridion can make hormonal birth control less effective. For at least 7 days after you receive this medicine, use a non-hormonal back-up birth control (condom or diaphragm with spermicide) to prevent pregnancy. Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) may not be effective enough to prevent pregnancy during this time.

It is not known whether sugammadex passes into breast milk. Tell your doctor if you are breastfeeding.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Tell your medical caregivers right away if you have:

• flushing (sudden warmth, redness, or tingly feeling);
• itching;
• wheezing, trouble breathing;
• weak or shallow breathing; or
• slow heartbeats.

Common side effects of Bridion may include:

• nausea, vomiting;
• pain;
• headache; or
• low blood pressure.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Bridion is injected into a vein through an IV. A healthcare provider will give you this medicine in a single injection.

Your breathing, blood pressure, oxygen levels, heart rate, and other vital signs will be watched closely while you are receiving Bridion.

Bridion is used as a single dose and does not have a daily dosing schedule.

In a medical setting an overdose would be treated quickly.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Tell your doctor about all your current medicines, especially:

• toremifene;
• hormonal birth control--birth control pills, injections, implants, skin patches, vaginal rings, or hormonal IUDs; or
• medicine used to prevent blood clots--warfarin, dabigatran (Pradaxa), rivaroxaban (Xarelto), and others.

This list is not complete. Other drugs may affect Bridion, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.