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Buckleys Mixture

Generic name: dextromethorphan

Brand names: Babee Cof, Buckley's Mixture Cough Suppressant, Children's Cough DM, Children's Robitussin 12 Hour Cough Relief, Cough DM, Cough Relief, Creomulsion, DayQuil Cough, Delsym, Delsym 12 Hour Cough Relief, Elixsure Cough, Father John's Medicine, Robafen Cough Liquidgels, Robitussin 12 Hour Cough Relief, Robitussin Long-Acting CoughGels, Robitussin Pediatric Cough Long-Acting, Scot-Tussin Diabetic, Buckleys Mixture

Last updated October 28, 2026 0 views
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What is Buckleys Mixture?

Buckleys Mixture is a cough suppressant that is used to treat cough caused by the common cold or flu.

Buckleys Mixture will not treat a cough caused by smoking, asthma, or emphysema.

There are many brands and forms of dextromethorphan available. Not all brands are listed on this leaflet.

Buckleys Mixture may also be used for purposes not listed in this medication guide.

How should I take Buckleys Mixture?

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms clear up.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

If you need surgery or medical tests, tell your surgeon or doctor ahead of time that you have taken Buckleys Mixture in the past few days.

Store at room temperature away from moisture, heat, and light. Do not freeze.

Warnings

Do not use Buckleys Mixture if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Before taking this medicine

Do not use Buckleys Mixture if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use Buckleys Mixture if you are allergic to it.

Ask a doctor or pharmacist if this medicine is safe to use if you have any medical conditions.

Buckleys Mixture should not be given to a child younger than 12 years old.

Ask a doctor before using this medicine if you are pregnant or breast-feeding.

This medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).

Buckleys Mixture side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Buckleys Mixture may cause serious side effects. Stop using Buckleys Mixture and call your doctor at once if you have:

  • severe nervousness, confusion;
  • severe dizziness or drowsiness;
  • blurred vision; or
  • painful or difficult urination.

Common side effects of Buckleys Mixture may include:

  • nausea, diarrhea, loss of appetite;
  • dizziness;
  • tingling; or
  • feeling restless.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What happens if I miss a dose?

Since cough or cold medicine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Avoid driving or hazardous activity until you know how Buckleys Mixture will affect you. Your reactions could be impaired.

Drinking alcohol can increase certain side effects of this medicine.

Ask a doctor or pharmacist before using over-the-counter medicines that may contain ingredients similar to Buckleys Mixture.

What other drugs will affect Buckleys Mixture?

Avoid using this medicine with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures). Ask a doctor or pharmacist before using any other medication, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed in this medication guide.

Common questions about Buckleys Mixture

What cold medicine can you take with diabetes?
If you have diabetes and you catch a cold or flu, there are over-the-counter (OTC) medicines that are safe for you to take to help alleviate your symptoms. Check out our suggestions for pain and fever relievers, cough and congestion medications and more. Remember to look for cold and flu medicines that are less likely to affect your blood sugar (glucose) levels, including sugar-free and alcohol-free options, or worsen any diabetes complications you may have. Continue reading
Does Mucinex help with Covid?
Mucinex does not prevent or cure COVID‑19, but it can help some people feel better by easing symptoms like chest congestion and cough. It should be used only for symptom relief and never as a substitute for COVID‑19–specific treatments, such as antivirals prescribed by your doctor. Continue reading

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
General medicine information Consumer-friendly language Source: Drugs.com

Content is provided for education and is not medical advice. See our medical disclaimer.