Cantil (Oral)

Mepenzolate is used to treat peptic ulcers. It works by reducing stomach acid production and bowel contractions. Mepenzolate is an anticholinergic agent.

This medicine is available only with your doctor's prescription.

It is very important for your doctor to check your progress during regular visits. This will help your doctor see if the medicine is working properly and decide if you should keep taking it.

This medicine may reduce sweating, which can cause your body temperature to rise. Be extra careful to avoid overheating during exercise or hot weather, as overheating may lead to heat stroke.

This medicine may cause dizziness, drowsiness, or blurred vision. Avoid driving, operating machinery, or doing anything else that could be dangerous until you know how this medicine affects you.

Contact your doctor immediately if you experience agitation, confusion, difficulty speaking, trouble sleeping, or unusual changes in mood or behavior, or if you see, hear, or feel things that are not there. These may be nervous system side effects of the medicine.

Do not take other medicines unless your doctor has discussed them with you. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

In deciding to use a medicine, you and your doctor need to weigh the risks against the benefits. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you have, such as to foods, dyes, preservatives, or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatric

There have not been appropriate studies on how mepenzolate affects children. Its safety and effectiveness for kids have not been established.

Geriatric

Studies have not shown any specific problems in older adults that would limit the use of mepenzolate. However, older patients may have age-related issues with their kidneys, liver, or heart, which might require careful monitoring and possible changes to the dose when taking mepenzolate.

Breast Feeding

There are no adequate studies on the risk to infants when this medication is used during breastfeeding. Consider the potential benefits and risks before using this medication while breastfeeding.

Interactions with Medicines

Some medicines should never be used together. In other cases, two different medicines may be used together even if there could be an interaction. If you are taking this medicine, it is very important for your healthcare professional to know if you are taking any of the medicines listed below. The following interactions are significant but may not include all possibilities.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide against prescribing this medication or may change some of your other medicines.

• Potassium Citrate

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in some cases. If both medicines are prescribed together, your doctor may adjust the dose or frequency for one or both medicines.

• Amantadine
• Amifampridine
• Buprenorphine
• Bupropion
• Clozapine
• Codeine
• Donepezil
• Glucagon
• Glycopyrrolate
• Glycopyrronium Tosylate
• Methacholine
• Oxycodone
• Quetiapine
• Revefenacin
• Scopolamine
• Secretin Human
• Tapentadol
• Tiotropium

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken at or around meal times or with certain foods, as interactions may happen. Drinking alcohol or using tobacco with some medicines may also lead to interactions. Talk to your healthcare professional about how to use your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical issues may impact the use of this medicine. Be sure to tell your doctor if you have any other medical problems, especially:

• Autonomic neuropathy (nerve issue) or
• Heart rhythm problems (e.g., arrhythmia) or
• Hiatal hernia with reflux (stomach issue) or
• Hypertension (high blood pressure) or
• Tachycardia (fast heart rate)—Use with caution. This may worsen these conditions.

• Congestive heart failure or
• Enlarged prostate or
• Heart disease (e.g., coronary artery disease) or
• Hyperthyroidism (overactive thyroid) or
• Ulcerative colitis—Use with caution. This may worsen side effects.

• Glaucoma or
• Myasthenia gravis or
• Paralytic ileus (bowel movement issue) or
• Stomach or bowel blockage (e.g., achalasia, intestinal atony, pyloroduodenal stenosis, toxic megacolon) or
• Urinary bladder blockage—Should not be used in patients with these conditions.

• Tartrazine sensitivity—Cantil® contains tartrazine, which may cause allergic reactions in people with this sensitivity.

Along with its needed effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, you may need medical attention.

Check with your doctor right away if any of the following side effects occur:

Incidence not known

• Blurred vision
• confusion
• cough
• decrease in the frequency of urination
• decrease in urine volume
• difficulty in passing urine (dribbling)
• difficulty with swallowing
• dizziness
• fast, pounding, or irregular heartbeat or pulse
• hives, itching, or skin rash
• painful urination
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• tightness in the chest
• unusual tiredness or weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome, or if you have any questions about them:

Incidence not known

• Bloated feeling
• decreased interest in sexual intercourse
• decreased sweating
• difficulty having a bowel movement (stool)
• drowsiness
• inability to have or keep an erection
• loss in sexual ability, desire, drive, or performance
• loss of taste
• nervousness
• trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Cantil

Pharmacologic Class: Antimuscarinic

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance for side effects.

Take this medicine with meals and at bedtime.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets):For treatment of peptic ulcer: Adults—25 or 50 milligrams (mg) 4 times a day. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.