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Cefpodoxime

Generic name: cefpodoxime

Brand names: Vantin

Used for gonorrhea
Last updated November 1, 2026 0 views
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What is cefpodoxime?

Cefpodoxime is a cephalosporin (SEF a low spor in) antibiotic that treats infections caused by bacteria. This includes infections of the sinuses, throat, ears, skin, bladder, or lungs.

Cefpodoxime is also used to treat gonorrhea.

Cefpodoxime may also be used for reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I take cefpodoxime?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take a cefpodoxime tablet with food.

You may take cefpodoxime oral suspension (liquid) with or without food.

Shake the liquid before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection resistant to medication. Cefpodoxime will not treat a viral infection (flu or common cold).

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using cefpodoxime.

Store the tablets at room temperature away from moisture and heat.

Store the liquid in a tightly-closed bottle in the refrigerator. Do not freeze. Throw away any unused liquid after 14 days.

This section was rewritten for readability and reviewed for meaning.

Warnings

You should not use cefpodoxime if you have ever had a severe allergic reaction to any type of cephalosporin antibiotic (Omnicef, Keflex, and others).

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not take cefpodoxime if you are allergic to cefpodoxime or any other cephalosporin antibiotic (cefdinir, cefalexin, Keflex, Omnicef, and others).

Tell your doctor if you have ever had:

  • kidney disease;
  • urination problems;
  • a stomach or intestinal disorder such as colitis; or
  • an allergy to any type of penicillin.

Tell your doctor if you are pregnant.

You should not breastfeed while using cefpodoxime.

Cefpodoxime is not approved for use by anyone younger than 2 months old.

This section was rewritten for readability and reviewed for meaning.

Cefpodoxime side effects

Get emergency medical help if you have signs of an allergic reaction (hives, trouble breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, a red or purple skin rash that spreads and causes blistering and peeling).

Cefpodoxime may cause serious side effects. Call your doctor right away if you have:

  • severe stomach pain, diarrhea that is watery or bloody (even if it happens months after your last dose);
  • fever, chills, sore throat, mouth sores, swollen glands, joint pain, or not feeling well;
  • a seizure; or
  • liver problems--upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of cefpodoxime may include:

  • diarrhea;
  • nausea, stomach pain;
  • headache;
  • vaginal itching or discharge; or
  • diaper rash in an infant using cefpodoxime.

This is not a complete list of side effects and others may happen. Call your doctor for medical advice about side effects. You can report side effects to FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is close to the time for your next dose. Do not take two doses at the same time.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, stomach pain, and diarrhea.

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect cefpodoxime?

Cefpodoxime can harm your kidneys, especially if you also use certain medicines for infections, cancer, osteoporosis, organ transplant rejection, bowel disorders, high blood pressure, or pain or arthritis (including Advil, Motrin, and Aleve).

Tell your doctor about all your other medicines, especially:

  • probenecid;
  • an antacid; or
  • a stomach acid reducer (Pepcid, Tagamet, and others).

This list is not complete. Other drugs may affect cefpodoxime, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.