Centany AT (Topical)

Mupirocin topical cream is used to treat secondarily infected traumatic skin lesions caused by specific bacteria. Mupirocin topical ointment is used to treat impetigo. This medicine works by killing bacteria or stopping them from growing.

This medicine is available only with your doctor's prescription.

If your skin infection does not get better in 3 to 5 days, or if it gets worse, contact your doctor.

This medicine may cause diarrhea, which can be severe in some cases. It may happen 2 months or more after you stop using this medicine. Do not take any medicine to treat diarrhea without checking with your doctor first. If you have any questions or if mild diarrhea continues or worsens, contact your doctor.

Contact your doctor immediately if you experience severe itching, a skin rash, burning, stinging, redness, swelling, or irritation on the skin.

In deciding to use a medicine, you and your doctor must consider the risks of taking the medicine compared to the benefits it may provide. For this medicine, keep the following in mind:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also let your healthcare professional know about any other allergies you may have, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies have not shown any specific problems in children that would limit the usefulness of mupirocin topical. However, the safety and effectiveness of mupirocin cream have not been established in children younger than 3 months, and mupirocin ointment in children younger than 2 months.

Geriatric

Studies have not found specific problems in the elderly that would limit the usefulness of mupirocin topical cream. There is no information available on how age affects the effects of mupirocin topical ointment in older adults. Safety and efficacy have not been established.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Weigh the potential benefits against the potential risks before using this medication during breastfeeding.

Interactions with Medicines

Some medicines should not be used together, while in other cases two different medicines may be used together even if an interaction might occur. In these situations, your doctor may adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicines.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or specific types of food due to possible interactions. Using alcohol or tobacco with some medicines may also lead to interactions. Discuss with your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical issues may affect the use of this medicine. Be sure to tell your doctor if you have any other medical problems, especially:

• Diarrhea—Use with caution. May worsen this condition.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

• Burning, stinging, or pain at the site where you applied the medicine

Rare

• Blistering, crusting, irritation, itching, or reddening of the skin
• canker sores
• cracked, dry, scaly skin
• pain, swelling, tenderness, warmth of the skin
• sores, ulcers, or white spots on the lips or tongue or inside the mouth

Incidence not known

• Abdominal or stomach tenderness
• cough
• difficulty swallowing
• dizziness
• fast heartbeat
• fever
• hives or welts, itching, or skin rash
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• redness of the skin
• severe abdominal or stomach cramps and pain
• tightness in the chest
• unusual tiredness or weakness
• watery and severe diarrhea, which may also be bloody

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue, are bothersome, or if you have any questions about them:

Less common

• Headache
• nausea

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Bactroban
• Centany
• Centany AT

Available Dosage Forms:

• Ointment
• Cream

Therapeutic Class: Antibacterial

It is very important that you use this medicine only as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. To do so may cause unwanted side effects or skin irritation.

This medicine should only be used on the skin. Do not get it in your eyes, nose, mouth, or vagina. Do not use it on skin areas that have cuts, scrapes, or burns. If it does get on these areas, rinse it off right away with water.

To help clear up your skin infection completely, keep using mupirocin for the full time of treatment, even if your symptoms have disappeared. Do not miss any doses.

To use:

• Wash your hands with soap and water before and after using this medicine.
• Apply a thin layer to the affected area of the skin. Rub it in gently.
• After applying this medicine, the treated area may be covered with a gauze dressing if desired.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For topical dosage form (cream):For treatment of secondarily infected traumatic skin lesions: Adults and children 3 months of age and older—Apply three times a day for 10 days. Children younger than 3 months of age—Use and dose must be determined by your doctor.
• For topical dosage form (ointment): For treatment of impetigo: Adults and children 2 months of age and older—Apply three times a day. Children younger than 2 months of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

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