Chlorpheniramine and dextromethorphan

Chlorpheniramine is an antihistamine. Dextromethorphan is a cough suppressant.

Chlorpheniramine and dextromethorphan is a combination medicine used to treat sneezing, a runny nose, and a cough caused by the common cold.

Chlorpheniramine and dextromethorphan may also be used for reasons not mentioned in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Cough or cold medicine is only for short-term use until your symptoms go away.

Always follow the instructions on the medicine label when giving cough or cold medicine to a child. Do not use the medicine just to make a child sleepy. Misusing cough or cold medicines in very young children can lead to death.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

You must chew the chewable tablet before swallowing it.

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

If you need surgery or medical tests, tell your surgeon or doctor if you are currently using this medicine.

Store at room temperature away from moisture and heat. Do not freeze.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not use cough or cold medicine to make a child sleepy.

Do not use chlorpheniramine and dextromethorphan if you have taken an MAO inhibitor in the last 14 days. This could lead to a serious drug interaction. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not use this medicine if you are allergic to chlorpheniramine or dextromethorphan.

Ask a doctor or pharmacist if this medicine is safe for you if you have:

• glaucoma;
• an enlarged prostate;
• urination problems; or
• a cough with mucus, or a cough caused by smoking, asthma, emphysema, or chronic bronchitis.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

This medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).

Get emergency medical help if you have signs of an allergic reaction: hives; trouble breathing; swelling of your face, lips, tongue, or throat.

Stop using chlorpheniramine and dextromethorphan and call your doctor right away if you have severe drowsiness.

Older adults may be more likely to experience side effects such as dry mouth, constipation, and confusion.

Common side effects of chlorpheniramine and dextromethorphan may include:

• dizziness, drowsiness;
• dry mouth, nose, or throat;
• constipation;
• blurred vision; or
• feeling restless or excited (especially in a child).

This is not a complete list of side effects and others may happen. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Usual Pediatric Dose for Cough and Nasal Congestion:

Chlorpheniramine-dextromethorphan 1 mg-5 mg oral tablet, chewable:>=6 <12 yrs: 2 tablets orally, chewed or dissolved before swallowing, every 4 to 6 hours not to exceed 6 doses daily.Chlorpheniramine-dextromethorphan 1 mg-5 mg/5 mL oral liquid:>=6 <12 yrs: 10 mL orally every 4 to 6 hours not to exceed 6 doses daily.Chlorpheniramine-dextromethorphan 1 mg-7.5 mg/5 mL oral liquid:>=6 <12 yrs: 10 mL orally every 6 hours not to exceed 4 doses daily.

Since cough or cold medicine is taken as needed, you might not have a set dosing schedule. If you miss a dose and it is close to the time for your next dose, skip the missed dose. Do not take two doses at the same time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

• Avoid driving or hazardous activity until you know how chlorpheniramine and dextromethorphan will affect you. Your reactions could be impaired.

• Avoid drinking alcohol while taking this medicine.

• Ask a doctor or pharmacist before using other cough or cold medicines that may contain similar ingredients.

Do not use this medicine with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures). Ask a doctor or pharmacist before using any other medication, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed in this medication guide.