Cinobac (Oral)

Cinoxacin is used to prevent and treat infections in the urinary tract. It will not work for other types of infections, colds, flu, or other viral infections.

Cinoxacin is available only with your doctor's prescription.

If your symptoms do not improve within a few days, or if they get worse, contact your doctor.

This medicine may cause some people to feel dizzy. Make sure you know how this medicine affects you before you drive, operate machinery, or do anything else that could be risky if you are dizzy. If this side effect is particularly bothersome, consult your doctor.

Some people taking cinoxacin may become more sensitive to sunlight than usual. Even short exposure to sunlight can lead to severe sunburn, skin rash, redness, itching, or changes in skin color, or vision problems. When you start taking this medicine:

• Avoid direct sunlight, especially between 10:00 a.m. and 3:00 p.m., if possible.
• Wear protective clothing, including a hat and sunglasses.
• Use a sunblock with a skin protection factor (SPF) of at least 15. Some patients may need a product with a higher SPF, especially if they have fair skin. If you have questions about this, talk to your health care professional.
• Do not use a sunlamp or tanning bed or booth.

If you have a severe reaction to the sun, contact your doctor.

In deciding to use a medicine, you and your doctor will need to weigh the risks against the benefits. For this medicine, consider the following:

Allergies

Let your doctor know if you have ever had an unusual or allergic reaction to this medicine or any others. Also inform your healthcare professional about any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has caused bone development problems in young animals, so it is not recommended for children up to 18 years of age.

Geriatric

Many medicines have not been specifically studied in older adults. Therefore, it may not be known if they work the same way as they do in younger adults. While there is no specific information comparing the use of cinoxacin in older adults with younger age groups, this medicine is not expected to cause different side effects or problems in older people than in younger adults.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Weigh the potential benefits against the potential risks before taking this medication during breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while others can be used together even if an interaction might occur. In these cases, your doctor may adjust the dose, or other precautions may be necessary. It is especially important for your healthcare professional to know if you are taking any of the medicines listed below. The following interactions are important and may not include all possible interactions.

Using this medicine with any of the following is usually not recommended, but may be necessary in some cases. If both are prescribed together, your doctor may change the dose or frequency of one or both medicines.

• Cholera Vaccine, Live
• Methotrexate

Using this medicine with any of the following may increase the risk of certain side effects, but using both may be the best treatment for you. If both are prescribed together, your doctor may change the dose or frequency of one or both medicines.

• Aminolevulinic Acid

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around the time of eating food or certain types of food because interactions may happen. Using alcohol or tobacco with certain medicines may also cause interactions. Talk to your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical problems may affect the use of this medicine. Make sure to tell your doctor if you have any other medical issues, especially:

• Brain and spinal cord disorders
• Convulsions
• Tendinitis—Cinoxacin may worsen these conditions

• Kidney disease—Patients with kidney disease may have a higher risk of side effects.

Along with its required effects, a medicine may cause some unwanted effects. Not all of these side effects may occur, but if they do, they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

• Skin rash, itching, redness, or swelling

Rare

• black, tarry stools
• bleeding gums
• blood in urine or stools
• Dizziness
• headache
• increased sensitivity of skin to sunlight
• pinpoint red spots on skin
• unusual bleeding or bruising

Incidence unknown

• Bone pain
• lower back or side pain
• pain, inflammation, or swelling in calves, shoulders, or hands
• painful, swollen joints
• seizures

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Diarrhea
• loss of appetite
• nausea
• stomach cramps
• vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Cinobac

Chemical Class: Non-Fluorinated Quinolone

Cinoxacin may be taken with food, unless you are otherwise directed by your doctor.

Do not give this medicine to infants or children under 18 years of age, unless otherwise directed by your doctor. It has been shown to cause bone development problems in young animals.

To help clear up your infection completely, keep taking this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

This medicine works best when there is a constant amount in the urine. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times, day and night. For example, if you are to take 4 doses a day, the doses should be spaced about 6 hours apart. If this interferes with your sleep or other daily activities, or if you need help in planning the best times to take your medicine, check with your health care professional.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For capsule dosage form: For the prevention of urinary tract infections: Adults—250 milligrams (mg) at bedtime for up to five months. Children up to 18 years of age—Use is generally not recommended because it may cause bone development problems. For the treatment of urinary tract infections: Adults—250 mg every six hours; or 500 mg every twelve hours for seven to fourteen days. Children up to 18 years of age—Use is generally not recommended because it may cause bone development problems.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.