Clear-Atadine D (Oral)

Loratadine and pseudoephedrine combination is used to help with allergy and cold symptoms, such as a runny or stuffy nose, sneezing, watery eyes, and itching in the eyes, nose, or throat. It also helps to reduce swelling in the nasal passages, making it easier to breathe through the nose.

This medicine is available without a prescription (OTC).

If your or your child's symptoms do not get better in 7 days, or if they get worse (with fever), contact your doctor.

Do not use this medicine if you have taken an MAO inhibitor (MAOI), including Eldepryl®, Marplan®, Nardil®, or Parnate® in the last 2 weeks.

In deciding to use a medicine, you and your doctor need to think about the risks of taking it against the benefits it may provide. Here are some important things to consider:

Allergies

Tell your doctor if you have ever had any strange or allergic reaction to this medicine or any other medicines. Also, inform your healthcare professional if you have other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies so far have not shown any specific problems that would limit the use of loratadine and pseudoephedrine combination in children 12 years of age and older. However, safety and effectiveness have not been established in children younger than 12 years of age.

Geriatric

There is no information available on how age affects the effects of loratadine and pseudoephedrine combination in older patients.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the baby when used during breastfeeding. However, there are no adequate studies in women to determine the risk to the infant when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together. In other cases, two different medicines may be used together even if there might be an interaction. In these situations, your doctor may want to adjust the dose, or other precautions may be needed. It is very important for your healthcare professional to know if you are taking any of the medicines listed below when you are using this medicine. The following interactions have been chosen based on their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may choose not to treat you with this medication or adjust some of the other medicines you take.

• Dihydroergotamine
• Furazolidone
• Iproniazid
• Isocarboxazid
• Linezolid
• Methylene Blue
• Moclobemide
• Nialamide
• Phenelzine
• Procarbazine
• Rasagiline
• Safinamide
• Selegiline
• Tranylcypromine

Using this medicine with any of the following medicines is usually not recommended but may be necessary in some cases. If both medicines are prescribed together, your doctor may adjust the dose or how often you use one or both of the medicines.

• Amiodarone
• Carbamazepine
• Guanethidine
• Iobenguane I 123
• Iobenguane I 131
• Methyldopa
• Midodrine
• Pitolisant

Interactions with Food/Tobacco/Alcohol

Some medicines should not be used at or around meal times or with certain types of food due to possible interactions. Using alcohol or tobacco with some medicines may also cause interactions. The following interactions have been selected based on their potential significance and are not necessarily all-inclusive.

Other Medical Problems

Other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical issues, especially:

• Diabetes or
• Heart disease or
• High blood pressure or
• Kidney disease or
• Liver disease or
• Thyroid problems or
• Trouble urinating caused by enlarged prostate—Use with caution. May make these conditions worse.

Along with its intended effects, a medicine may cause some unwanted effects. While not everyone will experience these side effects, if they do occur, they may require medical attention.

Some side effects may happen that usually do not need medical attention. These side effects may go away as your body gets used to the medicine. Your health care professional might also have suggestions to prevent or lessen some of these side effects. Talk to your health care professional if any of the following side effects persist, are bothersome, or if you have any questions about them:

Incidence not known

• Dizziness
• drowsiness
• nervousness
• trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Alavert-D 12-Hour
• Allergy & Congestion Relief
• Claritin-D
• Claritin-D 12-Hour
• Claritin-D 24-Hour
• Clear-Atadine D

Available Dosage Forms:

• Tablet, Extended Release
• Tablet, Extended Release, 24 HR
• Tablet, Extended Release, 12 HR

Therapeutic Class: Antihistamine, Less-Sedating/Decongestant Combination

Pharmacologic Class: Antihistamine, Less-Sedating

Chemical Class: Piperidine

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Follow the instructions on the medicine label.

Swallow the extended-release tablet whole with a full glass of water. Do not divide, crush, chew, or dissolve it.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For symptoms of allergies and cold: For oral dosage form (12 hour extended-release tablets): Adults and children 12 years of age and older—One tablet every 12 hours. Each tablet contains 5 milligrams (mg) loratadine and 120 mg pseudoephedrine. Do not take more than 2 tablets in 24 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor. For oral dosage form (24 hour extended-release tablets): Adults and children 12 years of age and older—One tablet once a day. Each tablet contains 10 milligrams (mg) loratadine and 240 mg pseudoephedrine. Do not take more than one tablet in 24 hours. Children younger than 12 years of age—Use and dose must be determined by your doctor.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Do not use this medicine if the blister pack is open or torn.