COVID-19 (12y+) vaccine, Mnexspike (2026-2027)

COVID-19 is a serious illness caused by a virus known as SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2). It spreads from person to person through the air.

COVID-19 can impact your lungs or other organs. Symptoms can range from mild to severe and may include fever, chills, cough, sore throat, shortness of breath, tiredness, body aches, headache, loss of taste or smell, runny or stuffy nose, nausea, vomiting, or diarrhea.

Mnexspike vaccine is used to prevent COVID-19 in people:

• age 65 and older; or
• 12 years through 64 years of age who have a health condition that increases their risk of severe COVID-19.

COVID-19 vaccine does not contain coronavirus and cannot give you COVID-19. This vaccine will not treat an active COVID-19 infection.

Like any vaccine, COVID-19 vaccine may not provide protection in every person.

Read all vaccine information sheets provided to you.

Mnexspike COVID-19 vaccine is given to people who are at least 12 years old as a single injection into a muscle.

A single dose of Mnexspike COVID-19 vaccine is given at least 3 months after the last dose of any COVID-19 vaccine.

The doctor or vaccination provider will decide if an immunocompromised person needs extra doses.

Continue to use infection control methods when you are in public or around others who may not have been vaccinated. This includes social distancing, hand-washing, using a protective face covering, disinfecting surfaces you touch often, and not sharing personal items with others.

Getting a COVID-19 vaccine will not make you test positive on a coronavirus test. However, once your body develops immunity to COVID-19, you could test positive on an antibody test (a test to check for immunity in the body from previous exposure to coronavirus).

It is not known how long this vaccine will protect you from getting COVID-19. It is also not known how long immunity will last in a person who has been infected with and recovered from COVID-19. The COVID-19 vaccine is still being studied, and all of its risks are not yet known. Updated federal public health recommendations may be found at https://www.cdc.gov/covid/index.html.

Getting infected with COVID-19 could be much more harmful to your health than getting this vaccine.

You should not get this vaccine if you have had a severe allergic reaction after a previous dose of MNEXSPIKE, SPIKEVAX, Moderna COVID-19 vaccine, or if you have had a severe allergic reaction to any ingredient in this vaccine.

If you are infected with COVID-19, are waiting for test results, or have been exposed to someone with COVID-19: you may not be able to receive this vaccine until you have no symptoms and/or your required quarantine period has ended. Getting this vaccine will not reduce your ability to spread COVID-19 to others if you are infected but have no symptoms.

Ask your doctor if you are unsure about any COVID-19 treatments you have received.

Tell your vaccination provider if you:

• have any allergies;
• have had inflammation in or around your heart (myocarditis or pericarditis);
• have a fever;
• have bleeding problems or are using a blood thinner;
• have a weak immune system caused by disease or by using certain medicines (this vaccine may not work as well if you are immunosuppressed);
• are pregnant, plan to become pregnant, or are breastfeeding;
• have received any other COVID-19 vaccine or if you are scheduled to receive a vaccine; or
• have fainted after getting an injection.

Get emergency medical help if you have signs of an allergic reaction: hives, trouble breathing, swelling of your face, lips, tongue, or throat.

The vaccination provider may want to keep you under observation for a short time after the injection, to ensure you do not have an allergic reaction or faint. You will receive prompt treatment if there is a reaction immediately after getting the vaccine.

Not all possible side effects are known. Getting infected with COVID-19 may be much more harmful to your health than getting this vaccine.

Some people (most often males aged 12 to 24 years) who received this vaccine experienced inflammation of the heart muscle or the lining around the heart after vaccination, usually within the first week. Seek medical attention immediately if you have the following symptoms, especially within the first two weeks:

• chest pain;
• shortness of breath; or
• fast or pounding heartbeats, fluttering in your chest.

Common side effects of COVID-19 (12y+) vaccine, Mnexspike may include:

• pain, redness, hardness, or swelling where the injection was given;
• fever, chills, nausea, vomiting, feeling tired;
• swelling or tenderness under the arm where the injection was given; or
• headache, muscle pain, joint pain.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

You may also use a smartphone-based program called V-safe to communicate with the Centers for Disease Control and Prevention (CDC) about any health issues you have after receiving a COVID-19 vaccine: www.cdc.gov/vsafe

Usual Adult Dose for Vaccination:

0.2 mL IM as a single dose, at least 3 months after the last dose of COVID-19 vaccineComments:-This vaccine is approved for use in patients who have been previously vaccinated with any COVID-19 vaccine and are 65 years and older OR 18 through 64 years of age with at least 1 underlying condition that places them at high risk for severe outcomes from COVID-19.Use: For active immunization to prevent COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Usual Pediatric Dose for Vaccination:

12 years and older: 0.2 mL IM as a single dose, at least 3 months after the last dose of COVID-19 vaccineComments:-This vaccine is approved for use in patients who have been previously vaccinated with any COVID-19 vaccine and are 12 through 17 years of age with at least 1 underlying condition that places them at high risk for severe outcomes from COVID-19.Use: For active immunization to prevent COVID-19 caused by SARS-CoV-2

Contact your vaccination provider or health department if you miss your dose.

An overdose of this vaccine is unlikely to happen.

Do not receive other vaccines without first consulting a healthcare professional.

Before getting this vaccine, inform your vaccination provider about all other vaccines you have had. Other medications may impact this vaccine, including prescription and over-the-counter medicines, vitamins, and herbal products. Let your doctor know about all other medicines you are taking.