Cruex (Topical)

Compound undecylenic acid is an antifungal medicine. It is used to treat certain types of fungal infections. However, it has mostly been replaced by newer and more effective medicines for treating fungal infections.

Compound undecylenic acid can be obtained without a prescription.

If your skin problem does not get better within 4 weeks, or if it gets worse, contact your health care professional.

To help prevent reinfection after using this medicine, you can use the powder or spray powder form of this medicine every day after bathing and drying your skin carefully.

In deciding to use a medicine, you and your doctor need to think about the risks of taking it compared to the benefits it can provide. Here are some important points to consider for this medicine:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, let your health care professional know if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

Compound undecylenic acid should not be used on children up to 2 years of age, unless your doctor says otherwise. There is no specific information available about using compound undecylenic acid topical preparations in children 2 years of age and older compared to other age groups, but this medicine is not expected to cause different side effects or problems in children 2 years of age and older than in adults.

Geriatric

Many medicines have not been specifically studied in older adults. So, it may not be clear if they work the same way they do in younger adults or if they cause different side effects or problems in older adults. There is no specific information comparing the use of compound undecylenic acid in the elderly with use in other age groups.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together even if there might be an interaction. In those situations, your doctor may adjust the dose, or other precautions may be necessary. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken at or around mealtime or with specific types of food due to potential interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. Talk to your healthcare professional about how your medicine may interact with food, alcohol, or tobacco.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• Skin irritation not present before use of this medicine

Other side effects not listed may also happen in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Blis-To-Sol
• Caldesene
• Cruex

Available Dosage Forms:

• Solution
• Cream
• Tincture
• Powder

Therapeutic Class: Antifungal

Before applying compound undecylenic acid, wash the affected and surrounding areas, and dry thoroughly. Then apply enough medicine to cover these areas.

Keep this medicine away from the eyes.

For patients using the cream form of this medicine:

• Apply cream generously to affected and surrounding areas. Rub in well.
• Do not use on pus-containing sores or on badly broken skin.

For patients using the powder form of this medicine:

• If the powder is used on the feet, sprinkle it between toes, on feet, and in socks and shoes.

For patients using the aerosol powder or aerosol foam form of this medicine:

• From a distance of 4 to 6 inches, spray the affected and surrounding areas. If the medicine is used on the feet, spray it between the toes also. The powder may also be sprayed in socks and shoes.
• Do not use this medicine around the eyes, nose, or mouth.
• Do not inhale the aerosol.
• Do not use near heat, near open flame, or while smoking.

To help clear up your infection completely, keep using this medicine for 2 weeks after burning, itching, or other symptoms have disappeared, unless otherwise directed by your doctor. Do not miss any doses.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For fungus infections: For aerosol foam, aerosol powder, ointment, powder, or solution dosage forms: Adults and children 2 years of age and over—Apply to the affected area(s) of the skin two times a day. Children up to 2 years of age—Use is not recommended. For cream dosage form: Adults and children—Apply to the affected area(s) of the skin as often as necessary.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

• How do I get rid of nail fungus?