Cyclandelate (Oral)

Cyclandelate is part of a group of medicines known as vasodilators. These medicines make blood vessels larger. Cyclandelate is used to treat issues caused by poor blood circulation.

This medicine was available only with your doctor's prescription.

Wyeth-Ayerst stopped distributing cyclandelate in April 1997.

It may take a while for this medicine to work. If you think the medicine is not working, do not stop taking it by yourself. Instead, talk to your doctor.

The helpful effects of this medicine may be lessened if you smoke.

Dizziness may happen, especially when you stand up from lying down or sitting or when you climb stairs. Getting up slowly may help. If this problem does not go away or gets worse, talk to your doctor.

In deciding to use a medicine, you need to consider the risks of taking it against the benefits it will provide. This decision will be made together with your doctor. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you may have, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on this medicine have only been conducted in adults, and there is no specific information comparing the use of cyclandelate in children with its use in other age groups.

Geriatric

Many medicines have not been specifically studied in older adults. Therefore, it may not be clear whether they work the same way they do in younger adults. While there is no specific information comparing the use of cyclandelate in older adults to other age groups, this medicine is not expected to cause different side effects or problems in older people than in younger adults.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together even if an interaction might happen. In these situations, your doctor may want to adjust the dose, or other precautions may be necessary. Inform your healthcare professional if you are taking any other prescription or non-prescription (over-the-counter [OTC]) medicines.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used around the time of eating food or specific types of food because interactions may occur. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical problems may affect the use of this medicine. Make sure to tell your doctor if you have any other medical issues, especially:

• Angina (chest pain) or
• Bleeding problems or
• Glaucoma or
• Hardening of the arteries or
• Recent heart attack or
• Recent stroke—The chance of unwanted effects may be increased.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may occur, but if they do, they may need medical attention.

Some side effects may happen that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue, are bothersome, or if you have any questions about them:

Less common

• Belching, heartburn, nausea, or stomach pain
• dizziness
• fast heartbeat
• flushing of face
• headache
• sweating
• tingling sensation in face, fingers, or toes
• weakness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

If this medicine upsets your stomach, it may be taken with meals, milk, or antacids.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets): For treating poor circulation: Adults—At first, 1.2 to 1.6 grams a day. This is taken in divided doses before meals and at bedtime. Then, your doctor will gradually lower your dose to 400 to 800 milligrams (mg) a day. This is divided into two to four doses. Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.