Dantrium Intravenous (Intravenous)

Dantrolene is used to prevent or treat a condition called malignant hyperthermia that can happen in some patients during or after surgery or anesthesia. Malignant hyperthermia includes symptoms like very high fever, fast and irregular heartbeat, and breathing difficulties. It is thought that the risk of developing malignant hyperthermia runs in families.

This medicine is available only with your doctor's prescription.

Your doctor will provide you with only a few doses of this medicine until your condition gets better, and then you will switch to an oral medicine that works the same way. If you have any questions about this, please talk to your doctor.

This medicine may cause drowsiness, dizziness, or muscle weakness in some people. Make sure you understand how this medicine affects you before driving, using machines, or doing anything else that could be risky if you feel dizzy or are not alert or well-coordinated.

In deciding to use a medicine, it's important to consider the risks of taking it against the benefits it may provide. This is a decision you and your doctor will make together. For this medicine, the following points should be considered:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medications. Also, let your healthcare professional know if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies conducted so far have not shown any specific problems in children that would limit the use of dantrolene.

Geriatric

While studies on how age affects the effects of dantrolene in older patients have not been conducted, no specific problems have been documented to date. However, elderly patients are more likely to have age-related kidney, liver, or heart issues, which may require caution when using dantrolene.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Consider the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other situations, two different medicines may be used together despite possible interactions. In these cases, your doctor may adjust the dose or take other precautions. It is crucial that your healthcare professional knows if you are taking any of the medicines listed below while receiving this medicine. The following interactions are selected based on their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is generally not recommended, but may be necessary in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both medicines.

• Alprazolam
• Amlodipine
• Amobarbital
• Aprobarbital
• Buprenorphine
• Butabarbital
• Butalbital
• Calcium Oxybate
• Carisoprodol
• Chloral Hydrate
• Chlordiazepoxide
• Chlorzoxazone
• Cinnarizine
• Clevidipine
• Clobazam
• Clonazepam
• Clorazepate
• Diazepam
• Diltiazem
• Estazolam
• Ethchlorvynol
• Felodipine
• Flunitrazepam
• Flurazepam
• Halazepam
• Isradipine
• Ketazolam
• Levoketoconazole
• Lorazepam
• Lormetazepam
• Magnesium Oxybate
• Medazepam
• Mephenesin
• Mephobarbital
• Meprobamate
• Metaxalone
• Methadone
• Methocarbamol
• Methohexital
• Methotrexate
• Midazolam
• Nicardipine
• Nifedipine
• Nimodipine
• Nisoldipine
• Nitrazepam
• Oxazepam
• Oxycodone
• Pentobarbital
• Pexidartinib
• Phenobarbital
• Potassium Oxybate
• Prazepam
• Primidone
• Quazepam
• Secobarbital
• Sodium Oxybate
• Tapentadol
• Temazepam
• Thiopental
• Triazolam
• Verapamil

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken around meal times or with certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines can also lead to interactions. Talk to your healthcare professional about using your medicine with food, alcohol, or tobacco.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they might need medical attention.

Check with your doctor or nurse right away if you experience any of the following side effects:

Rare

• Blue lips and fingernails
• Chest pain
• Coughing that sometimes produces a pink frothy sputum
• Difficult, fast, noisy breathing, sometimes with wheezing
• Difficulty swallowing
• Dizziness
• Fast heartbeat
• Hives
• Increased sweating
• Itching
• Pale skin
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Shortness of breath
• Skin rash
• Swelling in legs and ankles
• Tightness in chest
• Tissue necrosis
• Unusual tiredness or weakness
• Wheezing

Incidence not known

• Changes in skin color, pain, tenderness, or swelling of foot or leg

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to suggest ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue, are bothersome, or if you have any questions about them:

Rare

• Flushing or redness of skin
• Unusually warm skin

Incidence not known

• Drowsiness
• Muscle weakness

Other side effects not listed may also happen in some patients. If you notice any other effects, consult with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Dantrium Intravenous
• Revonto
• Ryanodex

Available Dosage Forms:

• Powder for Solution
• Powder for Suspension

Therapeutic Class: Skeletal Muscle Relaxant, Direct Acting

Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given through a needle placed in one of your veins.