Dengue vaccine

This vaccine is used to prevent dengue in people 6 through 16 years old who have had dengue in the past and live in areas with a risk of dengue.

Like any vaccine, the dengue vaccine may not provide protection from disease in every person.

Dengue vaccine is given as an injection under the skin. You will get this vaccine at a doctor's office, clinic, or pharmacy.

The dengue vaccine is given in three doses, spaced 6 months apart. Talk to your doctor if you had a severe reaction after the first dose.

You may faint after receiving the dengue vaccine.

The dengue vaccine may affect the results of a tuberculosis test for up to one month after vaccination.

Use only as directed. Inform your doctor if you are taking other medicines or have any other medical conditions or allergies.

You should not use dengue vaccine if you are allergic to it, or if you have a weak immune system (from a disease or from using certain medicines).

Tell your doctor if:

• you have a weak immune system (from a disease or from using certain medicines); or
• you have never been infected with dengue before.

Tell your doctor if you are pregnant or plan to become pregnant. Having dengue during pregnancy may increase the risk of premature birth. The benefit of receiving dengue vaccine may outweigh any risks to the baby.

If you are pregnant, your name may be included in a pregnancy registry to monitor the effects of dengue vaccine on the baby.

Ask a doctor if it is safe to breastfeed while using this vaccine.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Dengue vaccine may cause serious side effects. Call your doctor right away if you have:

• signs and symptoms of dengue—high fever, severe stomach pain or tenderness, vomiting, bleeding gums, drowsiness, or hyperactivity.

Common side effects of dengue vaccine may include:

• pain, redness, swelling, or itching where the vaccine was injected;
• headache;
• not feeling well; or
• weakness.

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

Usual Pediatric Dose for Infection Prophylaxis:

6 to 16 years: 0.5 mL subcutaneously at months 0, 6, and 12 (3 doses total)Comments:-Not approved for use in individuals not previously infected by any dengue serotype or for whom information is unknown.-Limitation of use: The safety and effectiveness of this vaccine have not been established in individuals living in dengue nonendemic areas who travel to dengue endemic areas.Use: Prevention of dengue disease caused by dengue virus serotypes 1, 2, 3, and 4 in patients with laboratory-confirmed previous dengue infection and living in endemic areas

Be sure to get all recommended doses of this vaccine. You may not be fully protected against the disease if you do not complete the full series.

Since this vaccine is administered by a healthcare professional, an overdose of dengue vaccine is unlikely to happen.

Avoid mosquito bites. Speak with your doctor if you have any questions.

Before getting this vaccine, inform your doctor about all other vaccines you have had recently.

Also, let your doctor know if you have recently taken any drugs or treatments that can weaken your immune system, including:

• an oral, nasal, inhaled, or injectable steroid medicine;
• medications for psoriasis, rheumatoid arthritis, or other autoimmune disorders; or
• medicines for treating or preventing organ transplant rejection.

This list is not complete. Other drugs may interact with dengue vaccine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

• Why can't the dengue vaccine Dengvaxia be used in people who haven't already had dengue?