Dextromethorphan and pyrilamine

Dextromethorphan is a medicine that helps stop coughing, and pyrilamine is a medicine that helps relieve allergy symptoms.

Dextromethorphan and pyrilamine is a combination medicine used to treat cough, runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

Dextromethorphan and pyrilamine will not treat a cough that is caused by smoking, asthma, or emphysema.

Dextromethorphan and pyrilamine may also be used for purposes not listed in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use until your symptoms go away.

Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine just to make a child sleepy. Death can happen from the misuse of cough or cold medicines in very young children.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

Store at room temperature away from moisture and heat.

Do not use dextromethorphan and pyrilamine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

Do not use this medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.

You should not use this medicine if you are allergic to dextromethorphan or pyrilamine.

Do not use dextromethorphan and pyrilamine if you have taken an MAO inhibitor in the last 14 days. A dangerous drug interaction could happen. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

• chronic bronchitis or other breathing problems;
• heart problems;
• glaucoma;
• a thyroid disorder;
• diabetes; or
• an enlarged prostate and urination problems.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

This medicine may contain phenylalanine. Check the medication label if you have phenylketonuria (PKU).

Ask a doctor before giving this medicine to a child younger than 12 years old.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Dextromethorphan and pyrilamine may cause serious side effects. Stop using dextromethorphan and pyrilamine and call your doctor right away if you have:

• severe drowsiness or anxiety;
• little or no urinating; or
• a light-headed feeling, like you might pass out.

Common side effects of dextromethorphan and pyrilamine may include:

• drowsiness;
• nervousness; or
• feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Since dextromethorphan and pyrilamine is used as needed, you may not have a regular dosing schedule. If you miss a dose and it's almost time for your next dose, just skip the missed dose. Do not take two doses at the same time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

• Drinking alcohol with dextromethorphan and pyrilamine can cause side effects.

• Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Ask a doctor or pharmacist before using dextromethorphan and pyrilamine with any other medicines, especially those that can make you drowsy (like opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Inform your doctor about all the medicines you are currently taking and any medicine you begin or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.