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Upper respiratory combinations oral liquid (10 mg-1.25 mg/5 mL)

Dextromethorphan and triprolidine

Generic name: dextromethorphan and triprolidine

Brand names: Endal Liquid

Used for common cold
Last updated November 2, 2026 0 views
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What is dextromethorphan and triprolidine?

Dextromethorphan and triprolidine is a combination medicine that helps relieve cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

Dextromethorphan and triprolidine may also be used for other reasons that are not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I take dextromethorphan and triprolidine?

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use.

Do not give this medicine to a child without medical advice. Follow all directions when giving this medicine to a child. Do not use the medicine to make a child sleepy. Misuse of this medicine may cause death in very young children.

Measure liquid medicine with the supplied measuring device (not a kitchen spoon).

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

Store at room temperature away from moisture and heat.

This section was rewritten for readability and reviewed for meaning.

Warnings

Do not use this medicine if you are using or if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

Do not use dextromethorphan and triprolidine if you are using or have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

  • asthma or COPD, a cough with mucus, or a cough caused by smoking, emphysema, or chronic bronchitis;
  • high blood pressure or heart disease;
  • glaucoma;
  • diabetes;
  • urination problems due to an enlarged prostate; or
  • a thyroid disorder.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

This section was rewritten for readability and reviewed for meaning.

Dextromethorphan and triprolidine side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

dextromethorphan and triprolidine may cause serious side effects. Stop using dextromethorphan and triprolidine and call your doctor right away if you have:

  • dizziness;
  • nervousness; or
  • sleep problems (insomnia).

Common side effects of dextromethorphan and triprolidine may include:

  • drowsiness;
  • constipation; or
  • feeling restless or excited (especially in children).

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

What happens if I miss a dose?

dextromethorphan and triprolidine is used as needed. If you miss a dose while on a dosing schedule, skip it. Do not take two doses at the same time.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

  • Drinking alcohol with dextromethorphan and triprolidine can cause side effects.
  • Ask a doctor or pharmacist before taking other cough or cold medicines that may contain similar ingredients.

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect dextromethorphan and triprolidine?

Ask a doctor or pharmacist before using any other medicines that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Tell your doctor about all other medicines you use. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.