Dextromethorphan, pheniramine, and phenylephrine

Dextromethorphan, pheniramine, and phenylephrine is a combination medicine that helps relieve cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

Dextromethorphan, pheniramine, and phenylephrine may also be used for reasons not mentioned in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Cold or cough medicine is only for short-term use.

Do not give this medicine to a child without medical advice. Follow all directions when giving this medicine to a child. Do not use the medicine to make a child sleepy. Misuse of this medicine may cause death in very young children.

Measure liquid medicine with the supplied measuring device (not a kitchen spoon).

Call your doctor if your symptoms do not improve after 7 days, or if you have a fever, rash, or headaches.

Store at room temperature away from moisture and heat.

Do not use this medicine if you are using or have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur.

MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Do not use dextromethorphan, pheniramine, and phenylephrine if you are using or have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

• high blood pressure, heart disease;
• glaucoma;
• cough with mucus, or cough caused by emphysema or chronic bronchitis;
• urination problems due to an enlarged prostate;
• overactive thyroid; or
• diabetes.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Get emergency medical help if you have signs of an allergic reaction: hives, trouble breathing, swelling of your face, lips, tongue, or throat.

Stop using dextromethorphan, pheniramine, and phenylephrine and call your doctor right away if you have:

• dizziness;
• nervousness; or
• sleep problems (insomnia).

Less serious side effects may happen more often, and you might not experience any at all.

This is not a complete list of side effects and others may happen. Call your doctor for medical advice about side effects. You can report side effects to FDA at 1-800-FDA-1088.

Usual Adult Dose for Cold Symptoms:

Dextromethorphan/pheniramine/phenylephrine 20 mg-20 mg-10 mg oral powder:Dissolve 1 packet in 8 ounces of hot water and drink in 10 to 15 minutes. May repeat every 4 hours. Not to exceed 6 packets daily.

Usual Pediatric Dose for Cold Symptoms:

Dextromethorphan/pheniramine/phenylephrine 20 mg-20 mg-10 mg oral powder:>=12 yrs: Dissolve 1 packet in 8 ounces of hot water and drink in 10 to 15 minutes. May repeat every 4 hours. Not to exceed 6 packets daily.

dextromethorphan, pheniramine, and phenylephrine is taken as needed. If you miss a dose while on a schedule, skip it. Do not take two doses at the same time.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222.

Drinking alcohol with dextromethorphan, pheniramine, and phenylephrine can lead to side effects.

Talk to a doctor or pharmacist before using other cough or cold medicines that may have similar ingredients.

Do not drive or do anything dangerous until you understand how this medicine will affect you. Your reactions could be impaired.

Ask a doctor or pharmacist before using any other medicines that can make you sleepy (like opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Inform your doctor about all other medicines you are taking. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all potential interactions are listed here.