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Differin Daily Deep Cleanser

Generic name: benzoyl peroxide topical

Brand names: Acne Foaming Cream Face Cleanser, Acne-Clear, Benzac AC, Benzac AC Wash, Benzac W, BenzEFoam, BenzePrO, BPO Foaming Cloths, Clearplex, Clearskin, Differin Daily Deep Cleanser, Epsolay, Fostex Gel 10%, Inova, NeoBenz Micro, Neutrogena On Spot Acne Treatment, Oscion, Oscion Cleanser, Oxy Balance, Oxy Daily Wash

Last updated November 2, 2026 0 views
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What is Differin Daily Deep Cleanser?

Benzoyl peroxide kills bacteria. It also dries the skin a little, helping to remove extra oil and dirt easily.

Differin Daily Deep Cleanser (for the skin) is used to treat acne.

There are many brands and types of benzoyl peroxide available. Not all brands are mentioned in this leaflet.

Differin Daily Deep Cleanser may also be used for reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

Warnings

Benzoyl peroxide can cause a rare but serious allergic reaction or severe skin irritation. Stop using this medicine and seek emergency medical help if you experience: hives, itching; difficulty breathing, feeling light-headed; or swelling of your face, lips, tongue, or throat.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not use benzoyl peroxide if you are allergic to it, or if you have:

  • very sensitive skin.

Ask a doctor or pharmacist if Differin Daily Deep Cleanser is safe to use if you have any skin conditions or allergies.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Do not use this medicine on a child without medical advice.

This section was rewritten for readability and reviewed for meaning.

Differin Daily Deep Cleanser side effects

Differin Daily Deep Cleanser can cause a rare but serious allergic reaction or severe skin irritation. These reactions may happen just a few minutes after you apply the medicine, or within a day or longer afterward.

Stop using Differin Daily Deep Cleanser and get emergency medical help if you notice any signs of an allergic reaction: hives, itching; difficulty breathing, feeling light-headed; swelling of your face, lips, tongue, or throat.

Stop using benzoyl peroxide and call your doctor right away if you experience any of these side effects on the treated skin:

  • severe itching or burning;
  • severe stinging or redness;
  • swelling; or
  • peeling.

Common side effects of Differin Daily Deep Cleanser may include:

  • mild stinging or burning;
  • itching or tingling feeling;
  • skin dryness, peeling, or flaking; or
  • redness or other irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

How should I use Differin Daily Deep Cleanser?

Differin Daily Deep Cleanser can cause a rare but serious allergic reaction or severe skin irritation. Before you start using this medicine, you may choose to apply a "test dose" to see if you have a reaction. Apply a very small amount of the medicine to 1 or 2 small acne areas every day for 3 days in a row. If there is no reaction, begin using the full prescribed amount on the 4th day.

Use exactly as directed on the label, or as prescribed by your doctor.

Do not take by mouth. Topical medicine is for use only on the skin. Do not use on open wounds or on sunburned, windburned, dry, or irritated skin. Also avoid using Differin Daily Deep Cleanser on wounds or on areas of eczema. Wait until these conditions have healed before using this medication.

Wash your hands before and after applying this medication.

Clean and pat dry the skin to be treated. Apply benzoyl peroxide in a thin layer and rub in gently.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

You may need to shake the medicine just before each use.

Do not cover the treated skin area unless your doctor has told you to.

Benzoyl peroxide may bleach hair or fabrics. Avoid allowing this medication to come into contact with your hair or clothing.

It may take several weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Apply the medicine as soon as you can, but if it is almost time for your next dose, skip the missed dose. Do not apply two doses at one time.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical help or call the Poison Help line at 1-800-222-1222.

Rinse your eyes or mouth with water if Differin Daily Deep Cleanser gets in them.

Do not use skin products that may irritate your skin, such as harsh soaps, shampoos, hair dyes or permanent chemicals, hair removers or waxes, or skin products that contain alcohol, spices, astringents, or lime.

Avoid sunlight or tanning beds. Wear protective clothing and apply sunscreen (SPF 30 or higher) when you are outside.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect Differin Daily Deep Cleanser?

Applying benzoyl peroxide while using tretinoin topical medicine may lead to severe skin irritation. Brands that contain tretinoin include Avita, Renova, Retin-A, Tretin-X, and others.

Medicine used on the skin usually does not interact with other drugs you take. However, many drugs can interact with each other. Inform all your health care providers about all the medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

This section was rewritten for readability and reviewed for meaning.

Common questions about benzoyl peroxide

Does doxycycline work for acne?
Yes, doxycycline is an oral tetracycline antibiotic that works by slowing the growth of acne-producing bacteria and exhibiting anti-inflammatory effects. It is commonly prescribed by dermatologists for moderate-to-severe acne, and strongly recommended for acne in guidelines published by the American Academy of Dermatology (AAD). Continue reading

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Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.