Dobutamine and dextrose (Intravenous)

Dobutamine and dextrose combination injection is used to treat heart failure and helps the heart pump blood.

This medicine is to be given only by or under the supervision of your doctor.

It is very important for your doctor to monitor your progress closely while you are receiving this medicine to ensure it is working properly. Blood tests are needed to check for unwanted effects.

This medicine may raise your blood pressure or heart rate. Contact your doctor immediately if you experience blurred vision, dizziness, headache, nosebleeds, or numbness or tingling in your face, arms, or legs.

This medicine may cause serious allergic and skin reactions, including anaphylaxis, eosinophilia, and bronchospasms, which can be life-threatening and require immediate medical attention. Contact your doctor right away if you have black, tarry stools, chest pain or tightness, chills, cough, difficulty swallowing, dizziness, fast heartbeat, fever, hives, itching, skin rash, painful or difficult urination, puffiness or swelling of the eyelids or around your eyes, face, lips, or tongue, sore throat, sores, ulcers, or white spots on your lips or in your mouth, swollen glands, trouble breathing, unusual bleeding or bruising, or unusual tiredness or weakness.

This medicine may cause fluid overload, which can lead to electrolyte problems, overhydration, or pulmonary edema (fluid in the lungs). Talk with your doctor right away if you notice a decrease in urine output, noisy, rattling breathing, trouble breathing, swelling of your fingers, hands, feet, or lower legs, or weight gain.

Do not take other medicines unless you have discussed them with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

In deciding to use a medicine, you and your doctor will weigh the risks against the benefits. Consider the following:

Allergies

Tell your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also, inform your healthcare professional about any other allergies you may have, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Current studies have not shown any problems that would limit the use of dobutamine and dextrose combination injection in children.

Geriatric

Current studies have not shown any problems that would limit the use of dobutamine and dextrose combination injection in elderly patients. However, older patients are more likely to have age-related liver, kidney, or heart issues, which may require caution and dose adjustments.

Breast Feeding

There are no adequate studies to determine the risk to infants when using this medication during breastfeeding. Consider the potential benefits and risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together, while others may be used together with precautions. When receiving this medicine, it is important for your healthcare professional to know if you are taking any of the medicines listed below. The following interactions are significant but not all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change your other medicines.

• Dihydroergotamine
• Isocarboxazid
• Linezolid
• Tranylcypromine

Using this medicine with any of the following medicines is usually not recommended, but may be needed in some cases. If both are prescribed together, your doctor may adjust the dose or frequency of one or both medicines.

• Entacapone
• Ergonovine
• Methylergonovine
• Opicapone

Using this medicine with any of the following medicines may increase the risk of certain side effects, but using both may be the best treatment for you. If both are prescribed together, your doctor may change the dose or frequency of one or both medicines.

• Carvedilol

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around meal times because interactions may occur. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical issues may affect how this medicine works. Make sure to inform your doctor about any other medical problems you have, especially:

• Allergy to corn, corn products, or sulfites or
• Heart disease (e.g., idiopathic hypertrophic subaortic stenosis)—Should not be used in patients with these conditions.

• Diabetes or
• Heart rhythm problems or
• Hypertension (high blood pressure)—Use with caution. May worsen these conditions.

• Hypovolemia (low blood volume)—Should be corrected before starting this medicine.

Along with its necessary effects, this medicine may cause some unwanted effects. Not everyone will experience these side effects, but if they do occur, they may need medical attention.

Contact your doctor or nurse right away if any of the following side effects happen:

More common

• Dizziness
• Headache
• Increased heart rate
• Numbness or tingling in the arms or legs
• Trouble thinking, speaking, or walking
• Weakness

Less common

• Chest pain
• Fast, irregular, pounding, or racing heartbeat or pulse
• Trouble breathing

Incidence not known

• Back, tarry stools
• Bluish color
• Blurred vision
• Changes in skin color
• Chest discomfort or tightness
• Chills
• Confusion
• Cough
• Difficulty swallowing
• Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
• Fever
• Hives, itching, skin rash
• Painful or difficult urination
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Sore throat
• Sores, ulcers, or white spots on the lips or in the mouth
• Sweating
• Swelling of the fingers, hands, feet, or lower legs
• Swollen glands
• Unusual bleeding or bruising
• Weight gain

Some side effects may occur that usually do not require medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also have suggestions on how to prevent or reduce some of these side effects. Contact your health care professional if any of the following side effects persist, are bothersome, or if you have any questions about them:

Less common

• Nausea

Other side effects not listed may also happen in some patients. If you notice any other effects, reach out to your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Available Dosage Forms:

• Solution

Therapeutic Class: Cardiovascular Agent

Pharmacologic Class: Dobutamine

A nurse or other trained health professional will give you this medicine in a medical facility. It is given as a needle placed into one of your veins.