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Topical anti-infectives topical cream (10%)

Docosanol topical

Generic name: docosanol topical

Brand names: Abreva, Abreva Pump

Used for cold sores
Last updated November 2, 2026 0 views
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What is docosanol topical?

Docosanol topical (for the skin) is used to treat cold sores on the face and lips.

Docosanol may also be used for purposes not listed in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I use docosanol topical?

Use exactly as directed on the label, or as prescribed by your doctor.

Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.

Apply this medicine at the first sign of a cold sore, such as tingling, redness, itching, or a blister.

Wash your hands before and after applying docosanol topical.

Remove any cosmetics before applying docosanol topical. Apply enough medicine to completely cover the cold sore. Rub in gently and completely.

Call your doctor if your symptoms do not improve within 10 days, or if they get worse.

Store at room temperature away from moisture and heat. Do not freeze.

This section was rewritten for readability and reviewed for meaning.

Warnings

Follow all instructions on your medicine label and package. Inform all your healthcare providers about all your medical conditions, allergies, and all medicines you are using.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not use docosanol topical if you are allergic to it.

Ask a doctor before using docosanol topical if you are pregnant or breastfeeding.

Do not use this medicine on a child younger than 12 years old without medical advice.

This section was rewritten for readability and reviewed for meaning.

Docosanol topical side effects

Get emergency medical help if you notice signs of an allergic reaction: hives; feeling light-headed; wheezing, trouble breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects might happen more often, and you might not experience any at all.

This is not a complete list of side effects, and others may occur. Contact your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

Docosanol topical dosing information

Usual Adult Dose for Herpes Simplex:

Apply to affected area on face or lips 5 times a day beginning at the first sign of cold sore or fever blister (i.e., tingling)Use: For the treatment of cold sores or fever blisters on the face or lips

Usual Pediatric Dose for Herpes Simplex:

12 years or older: Apply to affected area on face or lips 5 times a day beginning at the first sign of cold sore or fever blister (i.e., tingling)Use: For the treatment of cold sores or fever blisters on the face or lips

What happens if I miss a dose?

Apply the medicine as soon as you can, but if it's nearly time for your next dose, skip the missed dose. Do not apply two doses at the same time.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

An overdose of docosanol topical is not expected to be harmful. If someone has accidentally swallowed the medication, seek emergency medical help or call the Poison Help line at 1-800-222-1222.

Do not share docosanol topical with anyone else, even if they have the same symptoms as you. Sharing this medicine may spread the infection.

Avoid getting this medicine in your eyes or mouth.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect docosanol topical?

Medicine applied to the skin is not likely to be influenced by other medications you take. However, many medications can interact with one another. Inform all your healthcare providers about every medicine you are using, including prescription and over-the-counter medicines, vitamins, and herbal products.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.