Drax Exametazime (Injection)

Technetium Tc 99m exametazime injection is a type of radiopharmaceutical. Radiopharmaceuticals are radioactive substances used to find and treat certain diseases or to examine how the body's organs work.

Technetium Tc 99m exametazime injection helps your doctor take images of your brain to check how well it is functioning. It is used for cerebral perfusion scintigraphy in stroke cases. This medicine is also used for leukocyte labeled scintigraphy to find stomach infections and inflammatory bowel disease.

This medicine should only be given by or under the direct supervision of a doctor who has special training in nuclear medicine.

It is very important that your doctor checks you closely while you are receiving this medicine. This will help your doctor see if the medicine is working correctly and decide if you should keep receiving it.

This medicine may cause serious allergic reactions. Check with your doctor right away if you have a rash, itching, swelling of the face, tongue, and throat, trouble breathing, or chest pain after you get the injection.

You will be exposed to radiation when you are given this medicine. Talk with your doctor if you have concerns about this.

In deciding to use a medicine, you and your doctor will weigh the risks of taking it against the benefits it may provide. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

Appropriate studies have not been conducted on how technetium Tc 99m exametazime injection affects children. Safety and effectiveness have not been established.

Geriatric

While appropriate studies on how technetium Tc 99m exametazime injection affects older adults have not been performed, there have been no specific problems documented for this age group. However, older patients are more likely to have age-related kidney issues, which may require caution and a change in dose for those receiving technetium Tc 99m exametazime injection.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Consider the potential benefits and risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should never be used together, while others can be used together even if an interaction may happen. In these cases, your doctor might adjust the dose or take other precautions. Inform your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicines.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken at or near mealtime or with certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional how your medicine interacts with food, alcohol, or tobacco.

Other Medical Problems

Other medical issues may affect how you can use this medicine. Make sure to tell your doctor if you have any other medical conditions, especially:

• Kidney disease—Use with caution. The effects may be stronger because the body may remove the medicine more slowly.

• Stomach problems (e.g., peritonitis) or
• Tumor—Use with caution. These conditions may affect the results of the test.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they may require medical attention.

Check with your doctor or nurse right away if any of the following side effects occur:

Rare

• Fever
• flushing or redness of the skin
• rash
• swelling or puffiness of the face
• unusually warm skin

Other side effects not mentioned may also occur in some patients. If you notice any other effects, consult with your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Ceretec
• Drax Exametazime

Available Dosage Forms:

• Kit

Therapeutic Class: Diagnostic Agent, Radiopharmaceutical Imaging

A doctor or other health professional will give you this medicine. This medicine is given through a needle placed in a vein.

You will need to urinate right away and as often as possible after receiving this medicine. Drink plenty of fluids before and after receiving this medicine so you will pass more urine.