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Drysol (topical)

Generic name: aluminum chloride hexahydrate (topical)

Brand names: Drysol, Xerac AC, Hypercare topical

Last updated November 2, 2026 0 views
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What is Drysol?

Drysol is an antiperspirant that affects the cells that make sweat.

Drysol (for the skin) is used to treat excessive sweating, known as hyperhidrosis.

Drysol may also be used for other reasons not mentioned in this medication guide.

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How should I use Drysol?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Do not take by mouth. Topical medicine is for use only on the skin. Do not use on broken skin, or skin that has recently been shaved.

For best results, apply the medicine at bedtime and leave it on your skin for 6 to 8 hours.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Wash and completely dry the skin before applying Drysol. If needed, dry the skin with a hair dryer on the warm setting.

Use the applicator provided with your medicine, or use a cotton ball to apply the medicine.

After using on the underarms: Wear a tee-shirt to keep the medicine from rubbing off onto your bed linens.

After using on the hands or feet: Wrap your hands or feet in plastic wrap and cover them with cotton gloves or socks. Leave the gloves or socks on while you sleep.

After using on the scalp: Wear a plastic shower cap to bed to keep the medicine from rubbing off onto your bed linens.

In the morning, remove the covering from treated skin areas and wash or shampoo the skin thoroughly, then towel dry. Do not reuse plastic wrap for additional applications. You may rinse and reuse the plastic shower cap.

Store the bottle tightly closed at room temperature, away from heat or open flame. This medicine contains alcohol and is flammable. The medicine will evaporate quickly when exposed to air.

Do not share this medicine with another person, even if they have the same symptoms you have.

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Warnings

Follow all instructions on your medicine label and package. Inform each of your healthcare providers about all your medical conditions, allergies, and all medicines you are taking.

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Before taking this medicine

You do not use Drysol if you are allergic to it.

Inform your doctor if you have ever had kidney disease.

Inform your doctor if you are pregnant or breastfeeding.

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Drysol side effects

Get emergency medical help if you have signs of an allergic reaction: hives; dizziness; chest tightness, difficult breathing; swelling of your face, lips, tongue, or throat.

Drysol may cause serious side effects. Call your doctor right away if you have:

  • severe burning, redness, or swelling of treated skin.

Common side effects of Drysol may include:

  • itching or mild burning of treated skin; or
  • tingling or prickly feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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What happens if I miss a dose?

Skip the missed dose and take your next dose at the usual time. Do not use two doses at the same time.

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What happens if I overdose?

An overdose of Drysol is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Do not apply any other deodorants or antiperspirants while you are using Drysol.

Avoid getting Drysol in your eyes, mouth, and nose, or on your lips. If contact does occur, rinse with water.

This medicine can stain certain types of fabric or metals that it comes in contact with.

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What other drugs will affect Drysol?

Medicine used on the skin is not likely to be affected by other drugs you use. However, many drugs can interact with each other. Inform each of your healthcare providers about all medicines you are using, including prescription and over-the-counter medicines, vitamins, and herbal products.

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Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.