Duramist Plus (Nasal)

Oxymetazoline helps to temporarily relieve nasal congestion or stuffiness caused by hay fever or other allergies, colds, or sinus issues.

Your doctor may also use this medicine for other conditions.

You can get this medicine without a prescription.

In deciding to use a medicine, you and your doctor need to consider the risks and benefits. For this medicine, think about the following:

Allergies

Inform your doctor if you have ever had an unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you have, such as to foods, dyes, preservatives, or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatric

Children may be more sensitive to the effects of oxymetazoline, which may increase the risk of side effects during treatment.

Geriatric

Many medicines have not been tested in older adults. Therefore, it may not be clear if they work the same way as in younger adults or if they cause different side effects or issues in older people. There is no specific information about the use of oxymetazoline in elderly patients.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication while breastfeeding. Consider the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while others may be used together even if an interaction could happen. In such cases, your doctor may adjust the dose or take other precautions. It is especially important that your healthcare professional knows if you are taking any of the following medicines. The following interactions are significant and may not include all possible interactions.

Using this medicine with any of the following medicines is usually not recommended but may be necessary in some cases. If both medicines are prescribed together, your doctor may adjust the dose or frequency of one or both medicines.

• Amineptine
• Amitriptyline
• Amitriptylinoxide
• Amoxapine
• Carteolol
• Carvedilol
• Clomipramine
• Desipramine
• Dibenzepin
• Doxepin
• Fentanyl Citrate
• Furazolidone
• Imipramine
• Iproniazid
• Isocarboxazid
• Labetalol
• Levobunolol
• Linezolid
• Lofepramine
• Melitracen
• Methylene Blue
• Metipranolol
• Moclobemide
• Nadolol
• Nialamide
• Nortriptyline
• Opipramol
• Oxprenolol
• Penbutolol
• Phenelzine
• Pindolol
• Practolol
• Procarbazine
• Propranolol
• Protriptyline
• Rasagiline
• Safinamide
• Selegiline
• Sotalol
• Tianeptine
• Timolol
• Tranylcypromine
• Trimipramine
• Zavegepant

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around the time of eating food or certain types of food due to possible interactions. Drinking alcohol or using tobacco with some medicines may also lead to interactions. Talk to your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical issues may affect how this medicine works. Be sure to tell your doctor if you have any other medical problems, especially:

• Dryness in the nose
• High blood pressure
• Tachycardia (fast heart rate)
• Difficulty urinating due to an enlarged prostate—These conditions may worsen with this medicine.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they may need medical attention.

Contact your doctor right away if you experience any of the following side effects:

• Blurred vision
• fast, irregular, or pounding heartbeat
• headache, dizziness, drowsiness, or lightheadedness
• high blood pressure
• increase in runny or stuffy nose
• nervousness
• trembling
• trouble sleeping
• weakness

Some side effects may happen that usually do not need medical attention. These side effects may go away as your body gets used to the medicine. Additionally, your health care professional may have suggestions to help prevent or lessen some of these side effects. Talk to your health care professional if any of the following side effects persist, are bothersome, or if you have any questions about them:

• Burning, dryness, or stinging inside the nose
• sneezing

Other side effects not listed may also occur in some patients. If you notice any other effects, consult your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• 4-Way Long Lasting
• Afrin
• Duramist Plus
• Duration
• Genasal
• Mucinex Full Force
• Mucinex Moisture Smart
• Nasacon
• Nasin
• Neo-Synephrine 12 Hour
• Nostrilla
• NRS-Nasal Relief
• Sinarest Nasal
• Vicks Sinex 12 Hour

Available Dosage Forms:

• Spray

Therapeutic Class: Decongestant

Chemical Class: Imidazoline

To use the nose drops:

• Blow your nose gently. Tilt the head back while standing or sitting up, or lie down on a bed and hang the head over the side. Place the drops into each nostril and keep the head tilted back for a few minutes to allow the medicine to spread throughout the nose.
• Rinse the dropper with hot water and dry with a clean tissue. Replace the cap right after use.
• To avoid spreading a cold or infection, do not use the container for more than one person and throw the container away after your cold is better.

To use the nose spray:

• Blow your nose gently. With the head upright, spray the medicine into each nostril. Sniff briskly while squeezing the bottle quickly and firmly. If needed, blow the nose gently again and repeat the spray process until the total dose is used.
• Rinse the tip of the spray bottle with hot water, taking care not to suck water into the bottle, and dry with a clean tissue. Replace the cap right after use.
• To avoid spreading a cold or infection, do not use the container for more than one person and throw the container away after your cold is better.

Use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for longer than 3 days without checking with your doctor. To do so may make your runny or stuffy nose worse and may increase the chance of side effects.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For nasal dosage form (nose drops or spray): For nasal congestion or stuffiness: Adults and children 6 years of age and older—Use 2 or 3 drops or sprays of 0.05% solution in each nostril every ten to twelve hours. Do not use more than two times in twenty four hours. Children up to 6 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

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