Emend for Injection

Emend for Injection is used with other medications to help prevent nausea and vomiting that may occur due to chemotherapy in adults and children who are at least 6 months old and weigh at least 6 kg (13 pounds).

Emend for Injection is not used to treat nausea and vomiting that you already have.

Emend for Injection may also be used for reasons not mentioned in this medication guide.

Tell your doctor about all your other medicines. Some drugs should not be used with Emend for Injection.

You should not use Emend for Injection if you are allergic to Emend for Injection or similar medicines such as aprepitant.

Some drugs should not be used with Emend for Injection. Your treatment plan may change if you also use pimozide.

Tell your doctor if you have ever had:

• to use a blood thinner (or a medicine called warfarin) and you have routine "INR" or prothrombin time tests; or
• liver disease.

It is not known if Emend for Injection will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using this medicine.

Emend for Injection can make hormonal birth control less effective, including birth control pills, injections, implants, skin patches, and vaginal rings. Use barrier birth control to prevent pregnancy: condom, diaphragm, cervical cap, or contraceptive sponge.

Ask your doctor about the best form of birth control while you are using Emend for Injection. Keep using the barrier form of birth control for 1 month after your last dose.

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Some side effects may happen during the injection. Tell your medical caregiver if you feel dizzy, nauseous, light-headed, itchy, sweaty, or if you have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

Emend for Injection may cause serious side effects. Call your doctor immediately if you have:

• pain, redness, swelling, burning, blistering, or changes in your skin where the medicine was injected; or
• a light-headed feeling, as if you might faint; or
• a fast or slow heart rate.

Common side effects of Emend for Injection may include:

• feeling weak or tired;
• fever;
• low blood cell counts;
• urinary tract infection;
• stomach pain or upset;
• diarrhea; or
• pain, weakness, or numbness in your arms or legs.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Emend for Injection is given as an infusion into a vein. A healthcare provider will give you this injection.

Emend for Injection is not for long-term use.

Emend for Injection is usually given on the first day of chemotherapy treatment.

Tell your medical caregivers if you feel any burning or pain when Emend for Injection is injected.

You may be given other medications to further help prevent nausea and vomiting.

You may need blood tests after receiving Emend for Injection if you also take a blood thinner called warfarin.

In a medical setting, it is unlikely that you will miss a dose of Emend for Injection.

In a medical setting, an overdose would be treated quickly.

Follow your doctor's instructions regarding any restrictions on food, drinks, or activities.

Sometimes it is not safe to use certain medicines together. Some drugs can change how much of other drugs are in your blood, which may increase side effects or make the medicines less effective.

Many drugs can affect Emend for Injection. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

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