EndaCof-DM

Brompheniramine is an antihistamine that lessens the effects of the natural chemical histamine in the body. Histamine can cause symptoms like sneezing, itching, watery eyes, and a runny nose.

Dextromethorphan is a cough suppressant. It changes the signals in the brain that start the cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Enlarged blood vessels can lead to nasal congestion (a stuffy nose).

EndaCof-DM is a combination medicine used to relieve cough, runny or stuffy nose, sneezing, itching, and watery eyes due to allergies, the common cold, or the flu.

EndaCof-DM will not treat a cough that comes from smoking, asthma, or emphysema.

EndaCof-DM may also be used for reasons not mentioned in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.

Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure liquid medicine with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not take for longer than 7 days in a row. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache or skin rash.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat.

Do not use this medicine if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not use EndaCof-DM if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could happen. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

To ensure this medicine is safe for you, tell your doctor if you have:

• asthma or COPD, cough with mucus, or cough caused by smoking, emphysema, or chronic bronchitis;
• a blockage in your digestive tract (stomach or intestines);
• high blood pressure or heart disease;
• liver or kidney disease;
• glaucoma;
• cough with mucus, or cough caused by emphysema or chronic bronchitis;
• an enlarged prostate or urination problems;
• pheochromocytoma (an adrenal gland tumor);
• an overactive thyroid; or
• if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

FDA pregnancy category C. It is not known if EndaCof-DM will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

This medicine can pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

This medicine may cause serious side effects. Stop using this medicine and call your doctor right away if you have:

• confusion, severe anxiety, hallucinations, tremors;
• weak or shallow breathing;
• feeling light-headed, like you might pass out;
• fast or pounding heartbeats;
• painful or difficult urination, little or no urinating;
• pale skin, weakness, easy bruising or bleeding, fever, chills, body aches; or
• increased blood pressure--severe headache, buzzing in your ears, chest pain, shortness of breath, uneven heartbeats.

Common side effects of EndaCof-DM may include:

• dizziness, drowsiness, headache;
• constipation, upset stomach, loss of appetite;
• blurred vision, double vision, dry eyes;
• sleep problems (insomnia); or
• dry mouth, nose, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Since EndaCof-DM is taken as needed, you might not have a regular dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is nearly time for your next scheduled dose. Do not take extra medicine to compensate for the missed dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Drinking alcohol can increase certain side effects of EndaCof-DM.

Ask a doctor or pharmacist before using any other cold, cough, allergy, or sleep medicine. Antihistamines and cough suppressants are found in many combination medicines. Taking certain products together can lead to taking too much of a certain drug. Check the label to see if a medicine has an antihistamine or cough suppressant.

This medication may cause blurred vision and may affect your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and see clearly.

Avoid overheating or becoming dehydrated during exercise and in hot weather. Brompheniramine and phenylephrine can reduce sweating, making you more likely to suffer from heat stroke.

Tell your doctor about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products. Some medicines can cause unwanted or dangerous effects when used together. Not all possible interactions are listed in this medication guide.

Taking EndaCof-DM with other drugs that make you sleepy or slow your breathing can make these effects worse. Ask your doctor before taking EndaCof-DM with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.