Enlicitide

Enlicitide is used along with diet and exercise to reduce "bad" cholesterol (low-density lipoprotein, or LDL) in adults with high cholesterol (hypercholesterolemia), including a genetic form known as heterozygous familial hypercholesterolemia.

Enlicitide may also be used for reasons not mentioned in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Enlicitide is usually taken once per day. Follow your doctor's instructions.

Take one tablet each morning on an empty stomach with water, black coffee, or plain tea, at least 30 minutes before eating food or drinking any other kind of liquid.

Swallow the tablet whole and do not crush, chew, or break it.

Your doctor may check your LDL ('bad') cholesterol while taking this medicine.

Store tightly closed at room temperature, away from moisture and heat. Keep the medicine in the original container, along with the packet or canister of moisture-absorbing preservative.

Use only as directed. Inform your doctor if you are taking other medicines, have other medical conditions, or have allergies.

Tell your doctor if you have or have ever had health problems or use other medications.

Enlicitide may harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using enlicitide.

Get emergency medical help if you have signs of an allergic reaction: hives, trouble breathing, swelling of your face, lips, tongue, or throat.

Common side effects of enlicitide may include:

• diarrhea; or
• dizziness.

This is not a complete list of side effects and others may happen. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Usual Adult Dose for Hypercholesterolemia:

20 mg orally once a dayUse: As an adjunct to diet and exercise, to reduce low-density lipoprotein cholesterol (LDL-C) in patients with hypercholesterolemia, including heterozygous familial hypercholesterolemia

Take the medicine as soon as you can, at least 30 minutes before eating or drinking anything other than water, black coffee, or plain tea. If it is nearly time for your next dose, skip the missed dose. Do not take 2 doses on the same day.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Follow your doctor's instructions about any limits on food, drinks, or activities.

Other drugs may affect enlicitide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you are using.