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Ophthalmic anti-infectives ophthalmic ointment (0.5%)

Erythromycin ophthalmic

Generic name: erythromycin ophthalmic

Brand names: Eyemycin, Ilotycin, Roymicin

Last updated November 2, 2026 0 views
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What is erythromycin ophthalmic?

Erythromycin is an antibiotic that fights bacteria.

Erythromycin ophthalmic (for the eyes) is used to treat bacterial infections of the eyes.

Erythromycin ophthalmic may also be used for reasons that are not mentioned in this medication guide.

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How should I use erythromycin ophthalmic?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Wash your hands before using eye medication.

To apply the ointment:

  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the ointment tube with the tip pointing toward this pocket. Look up and away from the tip.
  • Squeeze out a ribbon of ointment into the lower eyelid pocket without touching the tip of the tube to your eye. Blink your eye gently and then keep it closed for 1 or 2 minutes.
  • Use a tissue to wipe excess ointment from your eyelashes.
  • After opening your eyes, you may have blurred vision for a short time. Avoid driving or doing anything that requires you to see clearly.

Do not touch the tip of the ointment tube or place it directly on your eye. A contaminated tube tip can infect your eye, which could lead to serious vision problems.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of an infection that is resistant to medication. Erythromycin ophthalmic will not treat a viral or fungal eye infection.

Store at room temperature away from moisture and heat. Keep the tube tightly closed when not in use.

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Warnings

Follow all instructions on your medicine label and package. Inform each of your healthcare providers about all your medical conditions, allergies, and all medications you are using.

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Before taking this medicine

You should not use erythromycin ophthalmic if you are allergic to erythromycin.

  • a viral or fungal infection in your eye.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

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Erythromycin ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Erythromycin ophthalmic may cause serious side effects. Stop using erythromycin ophthalmic and call your doctor right away if you have:

  • severe burning, stinging, or irritation after using erythromycin ophthalmic; or
  • signs of eye infection—pain, swelling, severe discomfort, crusting or drainage, eyes becoming more sensitive to light.

Common side effects of erythromycin ophthalmic may include:

  • eye redness; or
  • mild eye irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Erythromycin ophthalmic dosing information

Usual Adult Dose for Ocular Infection:

Maintenance dose: 1 cm ribbon into the infected eye(s) up to 6 times dailyUse: For the treatment of superficial ocular infections

Usual Pediatric Dose for Ocular Infection:

Maintenance dose: 1 cm ribbon into the infected eye(s) up to 6 times dailyUse: For the treatment of superficial ocular infections

Usual Pediatric Dose for Neonatal Conjunctivitis:

Maintenance dose: 1 cm ribbon into the lower conjunctival sac of each eyeComment:-Do not flush the eye after instillation of the ointment.-Use a new tube for each infant.Use: For the prophylaxis of neonatal gonococcal or chlamydial ophthalmia

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is close to the time for your next dose. Do not use two doses at the same time.

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What happens if I overdose?

Seek emergency medical help or call the Poison Help line at 1-800-222-1222.

erythromycin ophthalmic may cause blurred vision and may affect your reactions. Avoid driving or doing anything risky until you understand how this medicine will affect you.

Do not use any other eye medications unless your doctor instructs you to.

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What other drugs will affect erythromycin ophthalmic?

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.