Florbetapir F 18

Florbetapir F 18 is a radioactive substance that helps create images of certain organs in the body during a PET (Positron Emission Tomography) scan.

Florbetapir F 18 is used along with a PET scan to find out how much plaque is in the brain. Plaque is a collection of certain proteins and damaged nerve cells that is commonly seen in the brains of people showing signs of Alzheimer's disease or other types of dementia.

Florbetapir F 18 may also be used for reasons not mentioned in this medication guide.

Florbetapir F 18 is given through an injection into a vein by a healthcare provider.

florbetapir F 18 is typically administered 30 to 50 minutes before your PET scan.

Receiving a radioactive agent such as florbetapir F 18 may increase your long-term risk of developing cancer. Talk with your doctor about your specific risk.

Receiving a radioactive agent may raise your long-term risk of getting cancer. Discuss your specific risk with your doctor.

Inform your doctor about all of your medical conditions.

Let your doctor know if you are pregnant.

Do not breastfeed for 24 hours after receiving florbetapir F 18. If you use a breast pump during this time, discard the milk and do not give it to your baby.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Common side effects of florbetapir F 18 may include:

• pain, bruising, swelling, or irritation where the medicine was injected;
• headache;
• joint or muscle pain;
• increased blood pressure;
• nausea; or
• feeling tired.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Usual Adult Dose for Positron Emission Tomography Imaging:

370 MBq (10 mCi), maximum 50 microgram mass dose, intravenously as a single bolus in a total volume of 10 mL or lessComments: The injection should be followed with an intravenous flush of 0.9% sterile sodium chloride.Use: PET imaging of the brain to estimate beta-amyloid neuritic plaque density in adult patients with cognitive impairment who are being evaluated for Alzheimer's Disease (AD) and other causes of cognitive decline.

Florbetapir F 18 is given as a single dose and does not require taking it daily.

In a medical setting, an overdose would be treated quickly.

Follow your doctor's instructions about any limits on food, drinks, or activities.

Other drugs may affect florbetapir F 18, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.