Gadoquatrane

Gadoquatrane is a contrast agent that has magnetic properties. It is used with magnetic resonance imaging (MRI) to make blood vessels, organs, and other non-bony tissues clearer on the MRI.

Gadoquatrane is used to help diagnose certain disorders of the body and central nervous system.

Gadoquatrane may also be used for reasons not mentioned in this medication guide.

Gadoquatrane is given through an injection into a vein by a healthcare provider.

You will be monitored for a short period to ensure you do not have an allergic reaction.

Your kidney function may need to be tested before you receive this medicine.

Gadoquatrane can cause a serious condition in people with advanced kidney disease. Before getting gadoquatrane, inform your doctor if you have kidney disease or if you are on dialysis. You may not be able to receive gadoquatrane. Also, let your doctor know if you have recently had any contrast agents similar to gadoquatrane.

You should not receive gadoquatrane if you are allergic to it.

Tell your doctor if you have or have ever had:

• asthma or allergies, including an allergic reaction to a contrast agent;
• high blood pressure;
• diabetes; or
• kidney disease (or if you are on dialysis).

Gadoquatrane can cause a life-threatening condition in people with advanced kidney disease. Ask your doctor about your individual risk.

Gadoquatrane can stay in your body for months or years after you receive gadoquatrane. It is not known whether this could cause any health problems in people whose kidneys work properly. Tell your doctor if you have had repeated scans with a contrast agent and provide the date of your last scan.

It is not known if gadoquatrane will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using this medicine.

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Gadoquatrane can cause a life-threatening condition in people with advanced kidney disease. Call your doctor right away if you have any symptoms of this condition, such as:

• burning, itching, swelling, scaling and tightening or hardening of your skin;
• skin redness or discoloration;
• muscle weakness;
• joint stiffness in your arms, hands, legs, or feet;
• pain; or
• tiredness, trouble moving.

Also call your doctor at once if you have:

• kidney problems--swelling, urinating less, feeling tired or short of breath.

Common side effects of gadoquatrane may include:

• pain, bruising, swelling, or irritation where the medicine was injected;
• dizziness, headache;
• nausea, vomiting;
• feeling hot;
• tingling; or
• itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Gadoquatrane is used as needed and is given in a medical setting, so it is unlikely that you will miss a dose.

In a medical setting, an overdose would be treated quickly.

Follow your doctor's instructions regarding any restrictions on food, drinks, or activities.

Other drugs may affect gadoquatrane, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.