Uses for Genacote

Aspirin extended-release capsules are used to reduce the risk of heart attack in patients with chronic coronary artery disease, including those with a history of heart attack or angina (severe chest pain). It is also used to lower the risk of having another stroke in patients who have had an ischemic stroke or transient ischemic attack.

This medicine is available only with your doctor's prescription.

This section was rewritten for readability and reviewed for meaning.

Precautions while using Genacote

It is very important for your doctor to check your progress while you are using this medicine. This will help your doctor see if the medicine is working properly and decide if you should keep taking it.

This medicine cannot be used to treat a heart attack. Use an immediate-release aspirin in that situation.

Make sure your doctor knows if you are pregnant or breastfeeding. Do not use this medicine during the later part of a pregnancy unless your doctor tells you to.

This medicine may increase the risk of bleeding problems, including stomach ulcers or bleeding. This usually happens if you are taking aspirin with certain medicines (for example, NSAIDs or blood thinners). Contact your doctor immediately if you have black, tarry stools, severe or ongoing stomach pain, unusual bleeding, bruising, weakness, or vomiting blood or material that looks like coffee grounds.

Do not take other medicines unless you have discussed them with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines, as well as herbal or vitamin supplements.

This section was rewritten for readability and reviewed for meaning.

Before using Genacote

In deciding to use a drug, the risks of using the drug must be weighed against the beneficial it will do. This is a decision you and your clinician will make. For this medicine, the following should be considered:

Allergies

Inform your clinician if you have ever had any unusual or allergic reaction to this drug or any other drugs. Additionally inform your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of aspirin extended-release capsules in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of aspirin extended-release capsules in the elderly.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before using this medication while breastfeeding.

Interactions with Medicines

Although certain drugs should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this drug, it is especially important that your healthcare professional know if you are using any of the drugs listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not advised. Your doctor may decide not to treat you with this drug or change some of the other drugs you take.

Abrocitinib
Defibrotide
Dichlorphenamide
Influenza Virus Vaccine, Live
Ketorolac

Using this medicine with any of the following medicines is typically not recommended, but may be required in some cases. If both drugs are prescribed together, your physician may change the dose or how frequently you use one or both of the medicines.

Acarbose
Aceclofenac
Acemetacin
Acenocoumarol
Acetazolamide
Alclometasone
Aldosterone
Alipogene Tiparvovec
Alteplase, Recombinant
Amcinonide
Amikacin
Amiloride
Amineptine
Amitriptyline
Amitriptylinoxide
Amoxapine
Amphotericin B
Amtolmetin Guacil
Anagrelide
Anisindione
Apixaban
Ardeparin
Argatroban
Bacitracin
Beclomethasone
Bemetizide
Bemiparin
Benazepril
Bendroflumethiazide
Benzthiazide
Betamethasone
Betrixaban
Bivalirudin
Brinzolamide
Bromfenac
Budesonide
Bufexamac
Bumetanide
Caplacizumab-yhdp
Capreomycin
Captopril
Celecoxib
Certoparin
Chlorothiazide
Chlorpropamide
Chlorthalidone
Choline Salicylate
Ciclesonide
Cilostazol
Cisplatin
Citalopram
Clobetasol
Clobetasone
Clocortolone
Clomipramine
Clonixin
Clopamide
Clopidogrel
Cortisone
Curcumin
Cyclopenthiazide
Cyclosporine
Cyclothiazide
Dabigatran Etexilate
Dalteparin
Danaparoid
Deflazacort
Desipramine
Desirudin
Desmopressin
Desonide
Desoximetasone
Desvenlafaxine
Dexamethasone
Dexibuprofen
Dexketoprofen
Diazoxide
Dibenzepin
Diclofenac
Dicumarol
Diflorasone
Diflucortolone
Diflunisal
Difluprednate
Digoxin
Dipyrone
Dorzolamide
Dothiepin
Doxepin
Droxicam
Duloxetine
Edoxaban
Emtricitabine
Enalapril
Enalaprilat
Enoxaparin
Eplerenone
Eptifibatide
Escitalopram
Ethacrynic Acid
Etodolac
Etofenamate
Etoricoxib
Etozolin
Felbinac
Fenoprofen
Fepradinol
Feprazone
Feverfew
Floctafenine
Flucloronide
Fludrocortisone
Flufenamic Acid
Flumethasone
Flunisolide
Fluocinolone
Fluocinonide
Fluocortin
Fluocortolone
Fluorometholone
Fluoxetine
Flurandrenolide
Flurbiprofen
Fluticasone
Fluvoxamine
Fondaparinux
Foscarnet
Fosinopril
Fosphenytoin
Furosemide
Gentamicin
Ginkgo
Glimepiride
Glipizide
Glyburide
Gossypol
Halcinonide
Halobetasol
Heparin
Hydrochlorothiazide
Hydrocortisone
Hydroflumethiazide
Ibrutinib
Ibuprofen
Imipramine
Indapamide
Indomethacin
Inotersen
Kanamycin
Ketoprofen
Lepirudin
Levomilnacipran
Lisinopril
Lithium
Lofepramine
Lornoxicam
Loteprednol
Loxoprofen
Lumiracoxib
Macimorelin
Meclofenamate
Medrysone
Mefenamic Acid
Melitracen
Meloxicam
Melphalan
Metformin
Methazolamide
Methotrexate
Methyclothiazide
Methylprednisolone
Metolazone
Milnacipran
Moexipril
Mometasone
Morniflumate
Nabumetone
Nadroparin
Naproxen
Nateglinide
Nefazodone
Neomycin
Nepafenac
Netilmicin
Nicorandil
Niflumic Acid
Nimesulide
Nimesulide Beta Cyclodextrin
Nortriptyline
Opipramol
Oxaprozin
Oxyphenbutazone
Paramethasone
Parecoxib
Parnaparin
Paromomycin
Paroxetine
Pemetrexed
Pentosan Polysulfate Sodium
Pentoxifylline
Perindopril
Phenindione
Phenprocoumon
Phenylbutazone
Phenytoin
Piketoprofen
Piracetam
Piretanide
Piroxicam
Plazomicin
Polythiazide
Potassium Citrate
Pranoprofen
Prasugrel
Prednicarbate
Prednisolone
Prednisone
Proglumetacin
Propyphenazone
Proquazone
Protein C
Protriptyline
Quinapril
Quinethazone
Ramipril
Repaglinide
Reteplase, Recombinant
Reviparin
Rimexolone
Rivaroxaban
Rofecoxib
Salicylic Acid
Salsalate
Selumetinib
Sertraline
Sodium Salicylate
Spectinomycin
Spirapril
Spironolactone
Streptomycin
Sulindac
Sulodexide
Tacrolimus
Tenofovir Alafenamide
Tenofovir Disoproxil Fumarate
Tenoxicam
Tianeptine
Tiaprofenic Acid
Ticagrelor
Ticlopidine
Tinzaparin
Tirofiban
Tobramycin
Tolazamide
Tolbutamide
Tolfenamic Acid
Tolmetin
Torsemide
Trandolapril
Trazodone
Treprostinil
Triamcinolone
Triamterene
Trichlormethiazide
Trimipramine
Turmeric
Valdecoxib
Valproic Acid
Vancomycin
Varicella Virus Vaccine, Live
Venlafaxine
Vilazodone
Vortioxetine
Warfarin
Xipamide

Using this medicine with any of the following medicines may cause an increased chance of certain side effects, but using both drugs may be the best therapy for you. If both medications are prescribed together, your physician may change the dose or how frequently you use one or both of the medicines.

Acebutolol
Atenolol
Betaxolol
Bisoprolol
Carteolol
Carvedilol
Celiprolol
Delapril
Esmolol
Imidapril
Labetalol
Levobunolol
Metipranolol
Metoprolol
Nadolol
Nebivolol
Nitroglycerin
Oxprenolol
Penbutolol
Pindolol
Probenecid
Propranolol
Sotalol
Streptokinase
Tamarind
Temocapril
Tenecteplase
Timolol

Interactions with Food/Tobacco/Alcohol

Certain drugs should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may as well cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased chance of certain adverse effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how frequently you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Ethanol

Other Medical Issues

The presence of other medical problems may affect the use of this medicine. Make sure you tell your clinician if you have any other medical issues, especially:

Allergy to nonsteroidal anti-inflammatory drugs (NSAIDs) or
Asthma with nasal polyps and rhinitis, history of or
Stomach ulcers or bleeding—Should not be used in patients with these conditions.

Kidney disease, serious or
Liver disease, serious—Avoid use in patients with these conditions.

This section was rewritten for readability and reviewed for meaning.

Side Effects of Genacote

Along with its needed effects, a medicine may cause some unwanted effects. Not all of these side effects may occur, but if they do, they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

Abdominal or stomach pain, cramping, or burning
black, tarry stools
bloody or cloudy urine
change in consciousness
chest pain or discomfort
confusion
constipation
convulsions, severe or continuing
dark urine
decreased frequency or amount of urine
diarrhea
difficult breathing
drowsiness
fainting
fast breathing
feeling that something terrible will happen
fever
general tiredness and weakness
greatly decreased frequency of urination or amount of urine
headache
heartburn
increased thirst
indigestion
irregular heartbeat
light-colored stools
loss of appetite
loss of consciousness
lower back or side pain
muscle cramping and weakness
muscle tremors
nausea or vomiting
nervousness
numbness or tingling in the hands, feet, or lips
panic
rapid, deep breathing
restlessness
seizures
skin rash
stomach cramps
swelling of the face, fingers, or lower legs
unusual bleeding or bruising
unusual tiredness or weakness
upper right abdominal or stomach pain
vomiting of blood or material that looks like coffee grounds
weakness or heaviness of the legs
weight gain
yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

Acid or sour stomach
anxiety
belching
dizziness
dry mouth
hyperventilation
irritability
shaking
stomach discomfort, upset, or pain
trouble sleeping
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

Ascriptin
Aspergum
Aspirtab
Bayer
Easprin
Ecotrin
Ecpirin
Entercote
Genacote
Halfprin
Ninoprin
Norwich Aspirin

Available Dosage Forms:

Capsule, Extended Release, 24 HR
Tablet, Chewable
Capsule, Liquid Filled
Tablet, Enteric Coated
Tablet

Therapeutic Class: Platelet Aggregation Inhibitor

Pharmacologic Class: NSAID

Chemical Class: Salicylate, Aspirin

This section was rewritten for readability and reviewed for meaning.

Proper use of Genacote

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Take the capsule with a full glass of water at the same time each day.

Swallow the extended-release capsule whole. Do not crush, break, or chew it.

Do not take Durlaza™ 2 hours before or 1 hour after drinking alcohol.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (extended-release capsules):To lower risk of heart attack and stroke: Adults—162.5 milligrams (mg) (one capsule) once a day. Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Frequently asked questions

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View more FAQ

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Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.

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Content is provided for education and is not medical advice. See our medical disclaimer.