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Genasal (Nasal)

Generic name: oxymetazoline

Brand names: 4-Way Long Lasting, Afrin, Duramist Plus, Duration, Genasal, Mucinex Full Force, Mucinex Moisture Smart, Nasacon, Nasin, Neo-Synephrine 12 Hour, Nostrilla, NRS-Nasal Relief, Sinarest Nasal, Vicks Sinex 12 Hour

Last updated October 30, 2025 0 views
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Uses for Genasal

Oxymetazoline is used to temporarily relieve nasal congestion or stuffiness caused by hay fever, other allergies, colds, or sinus problems.

Your doctor may also use this medicine for other conditions.

You can get this medicine without a prescription.

This section was rewritten for readability and reviewed for meaning.

Before using Genasal

In deciding to use a medicine, you need to consider the risks against the benefits. This is a decision you and your doctor will make together. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you may have, such as to foods, dyes, preservatives, or animals. For non-prescription products, carefully read the label or package ingredients.

Pediatric

Children may be more sensitive to the effects of oxymetazoline. This could increase the chance of side effects during treatment.

Geriatric

Many medicines have not been tested in older adults. Therefore, it may not be known if they work the same way they do in younger adults or if they cause different side effects or problems in older adults. There is no specific information about the use of oxymetazoline in the elderly.

Breast Feeding

There are no adequate studies in women to determine the risk to infants when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while others may be used together even if an interaction might occur. In these cases, your doctor may need to adjust the dose, or other precautions may be required. When taking this medicine, it is especially important for your healthcare professional to know if you are using any of the medicines listed below. The following interactions have been chosen for their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in some situations. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Amineptine
  • Amitriptyline
  • Amitriptylinoxide
  • Amoxapine
  • Carteolol
  • Carvedilol
  • Clomipramine
  • Desipramine
  • Dibenzepin
  • Doxepin
  • Fentanyl Citrate
  • Furazolidone
  • Imipramine
  • Iproniazid
  • Isocarboxazid
  • Labetalol
  • Levobunolol
  • Linezolid
  • Lofepramine
  • Melitracen
  • Methylene Blue
  • Metipranolol
  • Moclobemide
  • Nadolol
  • Nialamide
  • Nortriptyline
  • Opipramol
  • Oxprenolol
  • Penbutolol
  • Phenelzine
  • Pindolol
  • Practolol
  • Procarbazine
  • Propranolol
  • Protriptyline
  • Rasagiline
  • Safinamide
  • Selegiline
  • Sotalol
  • Tianeptine
  • Timolol
  • Tranylcypromine
  • Trimipramine
  • Zavegepant

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used around the time of eating food or consuming certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also cause interactions. Discuss with your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical problems may affect the use of this medicine. Be sure to tell your doctor if you have any other medical issues, especially:

  • Dryness in the nose or
  • High blood pressure or
  • Tachycardia (fast heart rate) or
  • Trouble urinating from an enlarged prostate—These may worsen these conditions.

This section was rewritten for readability and reviewed for meaning.

Side Effects of Genasal

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may happen, if they do, they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

  • Blurred vision
  • fast, irregular, or pounding heartbeat
  • headache, dizziness, drowsiness, or lightheadedness
  • high blood pressure
  • increase in runny or stuffy nose
  • nervousness
  • trembling
  • trouble sleeping
  • weakness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

  • Burning, dryness, or stinging inside of nose
  • sneezing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

  • 4-Way Long Lasting
  • Afrin
  • Duramist Plus
  • Duration
  • Genasal
  • Mucinex Full Force
  • Mucinex Moisture Smart
  • Nasacon
  • Nasin
  • Neo-Synephrine 12 Hour
  • Nostrilla
  • NRS-Nasal Relief
  • Sinarest Nasal
  • Vicks Sinex 12 Hour

Available Dosage Forms:

  • Spray

Therapeutic Class: Decongestant

Chemical Class: Imidazoline

This section was rewritten for readability and reviewed for meaning.

Proper use of Genasal

To use the nose drops:

  • Blow your nose gently. Tilt the head back while standing or sitting up, or lie down on a bed and hang the head over the side. Place the drops into each nostril and keep the head tilted back for a few minutes to allow the medicine to spread throughout the nose.
  • Rinse the dropper with hot water and dry with a clean tissue. Replace the cap right after use.
  • To avoid spreading a cold or infection, do not use the container for more than one person and throw the container away after your cold is better.

To use the nose spray:

  • Blow your nose gently. With the head upright, spray the medicine into each nostril. Sniff briskly while squeezing the bottle quickly and firmly. If needed, blow the nose gently again and repeat the spray process until the total dose is used.
  • Rinse the tip of the spray bottle with hot water, taking care not to suck water into the bottle, and dry with a clean tissue. Replace the cap right after use.
  • To avoid spreading a cold or infection, do not use the container for more than one person and throw the container away after your cold is better.

Use this medicine only as directed. Do not use more of it, do not use it more often, and do not use it for longer than 3 days without checking with your doctor. To do so may make your runny or stuffy nose worse and may increase the chance of side effects.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For nasal dosage form (nose drops or spray): For nasal congestion or stuffiness: Adults and children 6 years of age and older—Use 2 or 3 drops or sprays of 0.05% solution in each nostril every ten to twelve hours. Do not use more than two times in twenty four hours. Children up to 6 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Frequently asked questions

  • Does Mucinex help with Covid?

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.