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Mydriatics ophthalmic solution (5%)

Homatropine ophthalmic

Generic name: homatropine ophthalmic

Brand names: Homatropaire, Isopto Homatropine

Used for surgery uveitis
Last updated November 2, 2026 0 views
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What is homatropine ophthalmic?

Homatropine relaxes the muscles in the iris (the colored part) of your eye. Relaxing these muscles helps to enlarge your pupil.

Homatropine ophthalmic (for the eyes) is used to treat an eye condition called uveitis. homatropine ophthalmic is also used to widen your pupil before an eye exam, or to reduce pressure inside the eye after eye surgery.

Homatropine ophthalmic may also be used for reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I use homatropine ophthalmic?

Follow all directions on your prescription label. Do not use homatropine ophthalmic in larger or smaller amounts or for longer than recommended.

Do not use this medicine while wearing contact lenses. Homatropine ophthalmic may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses.

To treat uveitis, you may need to use homatropine ophthalmic every 3 to 4 hours.

Wash your hands before using the eye drops.

To apply the eye drops:

  • Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
  • Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute to keep the liquid from draining into your tear duct.
  • Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.
  • Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.

This section was rewritten for readability and reviewed for meaning.

Warnings

You should not use homatropine ophthalmic if you have glaucoma.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not use this medicine if you are allergic to homatropine, or if you have:

  • glaucoma, or
  • if your eye doctor has found changes in your eyes that could be signs of glaucoma.

It is not known if this medicine will harm an unborn baby. Tell your doctor if you are pregnant.

It is not known if homatropine ophthalmic passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

This section was rewritten for readability and reviewed for meaning.

Homatropine ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when homatropine is used in the eyes, side effects can happen if the medicine gets into your bloodstream.

Homatropine ophthalmic may cause serious side effects. Call your doctor immediately if you have:

  • eye swelling or redness, crusting or drainage;
  • red or puffy eyelids;
  • confusion, agitation; or
  • unusual thoughts or behavior.

Common side effects of homatropine ophthalmic may include:

  • stinging and burning after using the eye drops;
  • dry mouth, increased thirst; or
  • increased sensitivity of your eyes to light.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

Homatropine ophthalmic dosing information

Usual Adult Dose for Refraction:

Instill 1 to 2 drops into the eye(s) once; may repeat in 5 to 10 minutes if neededComments:-This drug has not been found by the US FDA to be safe and effective and the labeling has not been approved by the US FDA.

Usual Adult Dose for Uveitis:

Instill 1 to 2 drops into the eye(s) up to every 3 to 4 hoursComments:-This drug has not been found by the US FDA to be safe and effective and the labeling has not been approved by the US FDA.

Usual Pediatric Dose for Refraction:

Greater than 3 months: Instill 1 to 2 drops into the eye(s) once; may repeat in 5 to 10 minutes if neededComments:-This drug has not been found by the US FDA to be safe and effective and the labeling has not been approved by the US FDA.

Usual Pediatric Dose for Uveitis:

Greater than 3 months: Instill 1 to 2 drops into the eye(s) up to every 3 to 4 hoursComments:-This drug has not been found by the US FDA to be safe and effective and the labeling has not been approved by the US FDA.

What happens if I miss a dose?

Apply the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not use extra medicine to make up for the missed dose.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical help or call the Poison Help line at 1-800-222-1222 if someone has accidentally swallowed the medication.

Homatropine ophthalmic may cause blurred vision and can affect your thinking or reactions. Be cautious if you drive or do anything that needs you to be alert and see clearly.

Homatropine ophthalmic can increase your sensitivity to light. Protect your eyes when you are outside in sunlight.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect homatropine ophthalmic?

It is unlikely that other drugs you take by mouth or inject will affect homatropine ophthalmic used in the eyes. However, many drugs can interact with each other. Inform each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.