HyperTET S/D (Intramuscular)

Tetanus immune globulin is used to prevent tetanus infection (also known as lockjaw). Tetanus is a serious illness that causes convulsions (seizures) and severe muscle spasms that can be strong enough to cause bone fractures of the spine. Tetanus causes death in 30 to 40 percent of cases.

In recent years, two thirds of all tetanus cases have been in people 50 years of age and older. Having a tetanus infection in the past does not make you immune to tetanus in the future.

Tetanus immune globulin works by providing your body with the antibodies it needs to protect against tetanus infection. This is called passive protection. This passive protection lasts long enough to shield your body until it can produce its own antibodies against tetanus.

Tetanus immune globulin should only be given by or under the supervision of your doctor or other health care professional.

In deciding to use a medicine, you and your doctor must consider the risks of taking it against the benefits it may provide. Here are some important points to think about for this medicine:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you may have, such as to foods, dyes, preservatives, or animals. For non-prescription products, make sure to read the label or package ingredients carefully.

Pediatric

There is no specific information comparing the use of tetanus immune globulin in children to its use in other age groups. This medicine is not expected to cause different side effects or issues in children than it does in adults.

Geriatric

Many medicines have not been tested specifically in older adults. Therefore, it may not be known if they work the same way as in younger adults or if they cause different side effects or problems in older individuals. There is no specific information comparing the use of tetanus immune globulin in elderly patients with its use in other age groups. However, there is no evidence suggesting that the effects of tetanus immune globulin in older adults differ from those in younger people.

Breast Feeding

Studies in women indicate that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while in other cases, two different medicines may be used together even if there might be an interaction. In such cases, your doctor may adjust the dose or take other precautions. It is very important that your healthcare professional knows if you are taking any of the medicines listed below while using this medicine. The following interactions have been selected based on their potential significance and are not necessarily a complete list.

Using this medicine with any of the following medicines may increase the risk of certain side effects, but using both may be the best treatment for you. If both medicines are prescribed together, your doctor may adjust the dose or how often you use one or both of the medicines.

• Adenovirus Vaccine
• Dengue Tetravalent Vaccine, Live
• Influenza Virus Vaccine, Live
• Measles Virus Vaccine, Live
• Mumps Virus Vaccine, Live
• Poliovirus Vaccine, Live
• Rotavirus Vaccine, Live
• Rubella Virus Vaccine, Live
• Smallpox Vaccine
• Varicella Virus Vaccine, Live
• Yellow Fever Vaccine
• Zoster Vaccine, Live

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be taken around the time of eating food or certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical problems may affect the use of tetanus immune globulin. Make sure to inform your doctor if you have any other medical issues.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Rare

• Difficulty in breathing or swallowing
• hives
• itching, especially of soles or palms
• reddening of skin, especially around ears
• swelling of eyes, face, or inside of nose
• unusual tiredness or weakness, sudden and severe

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Baytet
• HyperTET S/D

Available Dosage Forms:

• Solution

Therapeutic Class: Immune Serum

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For injection dosage form: For preventing tetanus infection: Adults and children—250 units injected into a muscle.