IOSAT

iOSAT helps thin mucus and clear congestion in the chest and throat. It is used by people with breathing issues that might be worsened by thick mucus, such as asthma, chronic bronchitis, or emphysema.

iOSAT is taken during a nuclear radiation emergency to prevent radioactive iodine from getting into your thyroid gland. For this reason, the medicine is typically taken only once or twice.

iOSAT may also be used for other reasons not mentioned in this medication guide.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take with food or milk if iOSAT upsets your stomach.

Measure liquid medicine with the supplied measuring device (not a kitchen spoon). Mix the liquid with water, fruit juice, or milk before taking.

For thinning mucus in the chest and throat, iOSAT is usually taken 3 to 4 times each day. Follow your doctor's dosing instructions very carefully. Use this medicine only as long as needed to get the best results.

For thyroid protection after nuclear radiation exposure, take the medicine as soon as possible after instructed by public officials. If you are told to take a second dose, wait at least 24 hours after you took the first dose. Use only as many doses as public officials tell you. Taking more of this medicine will not make it work better or faster, and may increase the risk of side effects.

Follow all directions when giving this medicine to a child during a nuclear emergency. Doses are based on weight in children and teenagers.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using iOSAT.

Store at room temperature away from moisture, heat, and light.

iOSAT liquid may crystallize if it gets cold. To clear the crystals, shake the liquid or allow it to reach room temperature. Do not use if the liquid has turned brown or yellow. Call your pharmacist for new medicine.

Use only as directed. Inform your doctor if you are taking other medicines or have other medical conditions or allergies.

You should not use iOSAT if you are allergic to iodide or iodine.

You may not be able to use iOSAT for exposure to nuclear radiation if you have:

• thyroid nodules and heart problems;
• dermatitis herpetiformis (Duhring disease, itchy skin rash common with celiac disease); or
• inflammation of the small blood vessels (hypocomplementemic urticarial vasculitis, or HUV) that causes episodes of hives, itching, burning, and painful skin sores.

Tell your doctor if you have ever had:

• a thyroid disorder;
• Addison's disease (an adrenal gland disorder);
• heart disease;
• tuberculosis;
• bronchitis;
• kidney disease; or
• myotonia congenita (a genetic muscle disorder).

iOSAT is used in children only during a radiation emergency. Do not give iOSAT to a child without medical advice.

iOSAT can cause thyroid problems in both mother and baby when used during pregnancy. However, the benefit of taking this medicine to protect your thyroid from nuclear radiation exposure far outweighs any risks of thyroid harm.

Any pregnant or breastfeeding woman or infant who takes iOSAT should have their thyroid function checked after using this medicine. Seek medical care as soon as possible.

If you are breastfeeding, tell your doctor if you notice a skin rash, muscle weakness, yellowed skin, breathing problems, feeding problems, or unusual crying in the nursing baby.

Get emergency medical help if you notice signs of an allergic reaction: hives, rash; fever, swollen glands, joint pain; wheezing, difficulty breathing, trouble swallowing; swelling of your face, lips, tongue, or throat.

IOSAT may lead to serious side effects. Stop using iOSAT and contact your doctor immediately if you experience:

• fever, tiredness;
• swelling in your neck or throat (enlarged thyroid, or goiter);
• chest pain, irregular heartbeats;
• numbness, tingling, pain, weakness, or swelling in your hands or feet;
• a weak or heavy feeling in your legs; or
• bloody or tarry stools, coughing up blood, or vomit that looks like coffee grounds.

High doses or long-term use of potassium iodide may result in iodine poisoning. Inform your doctor if you have symptoms such as burning in your mouth or throat, a metallic taste, tooth or gum pain, drooling, severe headache, cold symptoms (stuffy nose, sneezing), eye irritation, or severe skin rash.

Common side effects of iOSAT may include:

• swelling or tenderness in your lower jaw;
• rash; or
• nausea, vomiting, diarrhea, upset stomach, or stomach pain.

This is not a complete list of side effects, and others may occur. Contact your doctor for medical advice regarding side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Take the medicine as soon as you remember, but if it is nearly time for your next dose, skip the missed dose. Do not take two doses at once.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Tell your doctor about all your other medicines, especially:

• lithium;
• a diuretic or "water pill";
• an "ACE inhibitor" heart or blood pressure medicine--benazepril, captopril, enalapril, fosinopril, lisinopril, moexipril, perindopril, quinapril, ramipril, trandolapril; or
• medication to treat overactive thyroid--methimazole, propylthiouracil (PTU), radioactive iodine.

This list is not complete. Other drugs may affect iOSAT, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.