Loargys

Loargys is used in adults and children 2 years and older to treat high levels of arginine in people who have a condition called arginase 1 deficiency (ARG1-D). Those using Loargys should also follow a special diet that limits protein.

Loargys may also be used for other reasons not mentioned in this medication guide.

Loargys can cause serious allergic reactions, such as anaphylaxis. It must be administered in a healthcare setting where severe allergic reactions can be treated promptly.

You should not use Loargys if you are allergic to it.

Tell your doctor if you have or have ever had health problems, use other medications, or have had any previous allergic reactions.

Tell your doctor if you are pregnant or breastfeeding.

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Some side effects may happen during the injection. Tell your medical caregiver if you feel dizzy, nauseous, light-headed, itchy, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

Common side effects of Loargys may include:

• vomiting;
• fever; or
• constipation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Loargys is injected into a vein usually once every week. A healthcare provider will give you this injection.

You may be given other medications to help prevent serious side effects or allergic reaction. Keep taking these medicines for as long as your doctor has prescribed.

You will be watched for a short time to make sure you do not have an allergic reaction.

After 8 weeks, your provider may switch you to injections under the skin at the same dose.

If you tolerate injections under the skin and your provider approves, you may be able to receive Loargys injections at home, but only under the supervision of a healthcare provider.

You will need regular blood tests to check your arginine levels and to monitor for side effects.

Doses are based on weight. Your dose may change if you gain or lose weight.

You may need to follow a special diet. Follow all instructions of your doctor or dietitian. Learn about the foods you should eat or avoid.

Call your doctor for instructions if you miss an appointment for your Loargys.

In a medical setting, an overdose would be treated promptly.

Follow your doctor's guidance regarding any limitations on food, drinks, or activities.

Other drugs may affect Loargys, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor about all other medicines you are using.