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Lomaira

Generic name: phentermine

Brand names: Adipex-P, Lomaira, Suprenza

Last updated November 2, 2026 0 views
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What is Lomaira?

Lomaira is similar to an amphetamine. This medicine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Lomaira is used along with diet and exercise to treat obesity, especially in people with risk factors such as high blood pressure, high cholesterol, or diabetes.

Lomaira may also be used for reasons not mentioned in this medication guide.

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How should I take Lomaira?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may change your dose from time to time. Use the medicine exactly as directed.

Lomaira is usually taken before breakfast, or 1 to 2 hours after breakfast. Follow your doctor's dosing instructions very carefully.

Never use Lomaira in larger amounts, or for longer than prescribed. Taking more of this medication will not make it work better and can cause serious, life-threatening side effects.

Lomaira is for short-term use only. The effects of appetite suppression may wear off after a few weeks.

Lomaira may be habit-forming. Misuse can lead to addiction, overdose, or death. Selling or giving away Lomaira is against the law.

Call your doctor right away if you think this medicine is not working as well, or if you have not lost at least 4 pounds within 4 weeks.

Do not stop using Lomaira suddenly, or you could experience unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

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Warnings

You should not take Lomaira if you have glaucoma, an overactive thyroid, serious heart issues, uncontrolled high blood pressure, advanced coronary artery disease, severe agitation, or a history of drug abuse.

Do not use this medicine if you have taken an MAO inhibitor in the last 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

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Before taking this medicine

You should not use Lomaira if you are allergic to it, or if you have:

  • a history of heart disease (coronary artery disease, heart rhythm problems, congestive heart failure, stroke);
  • severe or uncontrolled high blood pressure;
  • overactive thyroid;
  • glaucoma;
  • extreme agitation or nervousness;
  • a history of drug abuse; or
  • if you take other diet pills.

Do not use Lomaira if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Weight loss during pregnancy can harm an unborn baby, even if you are overweight. Do not use Lomaira if you are pregnant. Tell your doctor right away if you become pregnant during treatment.

You should not breast-feed while using Lomaira.

Tell your doctor if you have ever had:

  • heart disease or coronary artery disease;
  • a heart valve disorder;
  • high blood pressure;
  • diabetes (your diabetes medication dose may need to be adjusted); or
  • kidney disease.

Lomaira is not approved for use by anyone younger than 16 years old.

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Lomaira side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Lomaira may cause serious side effects. Call your doctor right away if you have:

  • feeling short of breath, even with mild activity;
  • chest pain, feeling like you might faint;
  • swelling in your ankles or feet;
  • pounding heartbeats or fluttering in your chest;
  • tremors, feeling restless, trouble sleeping;
  • unusual changes in mood or behavior; or
  • increased blood pressure—severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed.

Common side effects of Lomaira may include:

  • itching;
  • dizziness, headache;
  • dry mouth, bad taste;
  • diarrhea, constipation, stomach pain; or
  • increased or decreased interest in sex.

This is not a complete list of side effects, and others may happen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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What happens if I miss a dose?

Take the medicine as soon as you can, but if it is late in the day, skip the missed dose. Do not take two doses at the same time.

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What happens if I overdose?

Seek emergency medical help or call the Poison Help line at 1-800-222-1222. Taking too much Lomaira can be deadly.

Signs of an overdose may include confusion, panic, seeing or hearing things that are not there, extreme restlessness, nausea, vomiting, diarrhea, stomach cramps, feeling tired or depressed, irregular heartbeats, weak pulse, seizures, or slow breathing (breathing may stop).

Do not drive or engage in dangerous activities until you know how Lomaira will affect you. Your reactions might be affected.

Drinking alcohol with this medicine can lead to side effects.

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What other drugs will affect Lomaira?

Taking Lomaira with other diet medications like fenfluramine (Phen-Fen) or dexfenfluramine (Redux) can lead to a rare and serious lung condition called pulmonary hypertension. Do not take this medicine with any other diet medications without your doctor's advice.

Many medications can interact with Lomaira. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Inform your doctor about all your current medications and any new medicine you start or stop using.

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Common questions about Lomaira

Why am I tired on Phentermine?
Fatigue or tiredness can come as a result of sleepless nights or following a period of over-stimulation, however, adverse effects of phentermine also include drowsiness, fatigue, and reduced energy levels. If you’re feeling fatigued or lacking in energy while taking phentermine and the problem persists, you should consult your doctor as it may be that you have an undiagnosed medical condition.
Is phentermine safe to use?
Phentermine is safe to use when taken as prescribed by your doctor. Make sure your doctor knows about all of the other medicines you take, as well as any medical problems you have. It should not be taken along with other weight loss drugs. Though rare, high blood pressure has been reported in some patients. Phentermine should not be taken if: You have cardiovascular disease You are taking or recently stopped taking drugs known as monoamine oxidase inhibitors You have hyperthyroidism You have glaucoma You have a history of drug abuse or agitation You are pregnant or nursing You are sensitive to or had a reaction to other stimulant drugs
How long does it take to start losing weight on phentermine?
Phentermine should be prescribed as part of a weight loss plan that also includes exercise, modifying behavior and reducing calories. Phentermine is usually taken for 12 weeks or less. Weight loss effects depend on the dose of phentermine taken, as well as diet, exercise and other factors.
How long does phentermine stay in your system?
Phentermine stays in your system for approximately 4 days after you take it. It takes about 20 hours for half of the drug to leave your system. Many things affect how long it takes a drug to leave your system. These include your age, diet, how well your kidneys and liver are working and other factors.
How to take phentermine for the best results?
Take phentermine as directed by your doctor. It is usually taken first thing in the morning, before breakfast. It may also be taken 1 to 2 hours after eating breakfast. Phentermine is not usually taken at night because it can cause insomnia.
Is Phentermine approved for weight loss?
Phentermine is a drug approved for weight loss as part of a regimen of exercise, calorie restriction and behavior modification. Phentermine may be prescribed for short-term treatment in people who have a body mass index (BMI) of 30 kg/m2 or greater. It may also be prescribed to people who have a BMI of 27 kg/m2 or greater with other risk factors, such as high blood pressure, diabetes or high cholesterol. Some of the adverse effects of phentermine may include: Heart palpitations Raised blood pressure A feeling of restlessness Headaches Dry mouth Diarrhea Constipation Hives A higher or lower libido
How does phentermine work?
Phentermine affects the brain’s neurotransmitters. It is thought to cause weight loss by suppressing appetite. The exact way phentermine works to cause weight loss is not known. Phentermine belongs to the class of drugs known as sympathomimetic amines. These are more commonly known as stimulant drugs.
What drugs can cause serotonin syndrome?
Common drug classes that can cause serotonin syndrome include selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), and opioids like tramadol. Continue reading
Why is phentermine a controlled substance?
Phentermine is classified as a Schedule IV controlled substance by the DEA because it is a prescription stimulant medication with potential for abuse and dependence, though the risk is considered relatively low compared to other controlled substances. Continue reading

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Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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