M-Dryl

M-Dryl is an antihistamine that helps with sneezing, a runny nose, watery eyes, hives, skin rashes, itching, and other cold or allergy symptoms.

M-Dryl is also used to treat motion sickness, help with sleep, and address certain symptoms of Parkinson's disease. This sleep aid is not for children younger than 12 years old.

There are many brands and forms of diphenhydramine available. Not all brands are included in this leaflet.

M-Dryl may also be used for other reasons not mentioned in this medication guide.

Use M-Dryl exactly as directed on the label or as your doctor prescribes. M-Dryl is meant for short-term use until your symptoms go away.

Taking too much M-Dryl can cause serious heart issues, seizures, coma, or death.

Always follow the instructions on the medicine label when giving M-Dryl to a child. Do not use this medicine just to make a child sleepy. Misusing antihistamines in very young children can lead to death.

For motion sickness, take M-Dryl 30 minutes before you expect to be in a situation that could cause motion sickness (like a long car ride, flying, boat travel, amusement park rides, etc.). Continue taking this medicine with meals and at bedtime while you are in a motion-sickness situation.

As a sleep aid, take M-Dryl within 30 minutes before going to bed.

You must chew the chewable tablet before swallowing it.

Measure liquid medicine carefully. Use the dosing syringe provided or a medicine dose-measuring device (not a kitchen spoon).

Take an orally disintegrating tablet out of the package only when you're ready to use it. Place the tablet in your mouth and let it dissolve without chewing. Swallow several times as it dissolves.

Contact your doctor if the condition you are treating with M-Dryl does not get better, or if you have a fever along with a headache, cough, or skin rash.

Do not use M-Dryl for more than 2 weeks for sleep issues, or more than 7 days for cold or allergy symptoms.

M-Dryl can impact the results of allergy skin tests. Inform any doctor treating you that you are using M-Dryl.

Store at room temperature, away from moisture and heat.

Use M-Dryl exactly as directed. Taking too much M-Dryl can cause serious heart problems, seizures, coma, or death.

Do not use this medicine to make a child sleepy. M-Dryl sleep aid medicine is not for children younger than 12 years old.

You should not use M-Dryl if you are allergic to it.

Talk to a doctor or pharmacist if you have ever had:

• an enlarged prostate or trouble urinating;
• asthma, chronic obstructive pulmonary disease (COPD), or another breathing problem;
• glaucoma; or
• a thyroid disorder.

Ask a doctor before using this medicine if you are pregnant or breastfeeding. M-Dryl may reduce breast milk production.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

M-Dryl may cause serious side effects. Stop using M-Dryl and call your doctor right away if you have:

• severe drowsiness; or
• painful or difficult urination.

Side effects like dry mouth, constipation, and confusion may happen more often in older adults.

Common side effects of M-Dryl may include:

• drowsiness;
• dry eyes, blurred vision;
• dry mouth, nose, or throat;
• decreased urination;
• constipation;
• feeling restless or excited (especially in children); or
• daytime drowsiness or a "hangover" feeling after night-time use.

This is not a complete list of side effects, and others may happen. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Since M-Dryl is taken as needed, you might not have a regular dosing schedule. If you miss a dose and it's almost time for your next dose, just skip the missed dose. Do not take two doses at the same time.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222. Taking too much diphenhydramine can be deadly.

Signs of an overdose may include vomiting, confusion, extreme sleepiness, ringing in your ears, not urinating, very dry eyes and mouth, dilated pupils, rapid heart rate, shaking, restlessness, hallucinations, or seizures.

Avoid driving or doing anything dangerous until you know how M-Dryl will affect you. Your reactions might be slowed down.

Drinking alcohol can make some side effects of diphenhydramine worse.

Check with a doctor or pharmacist before using any other medicine that might have M-Dryl in it. This includes medicines for sleep, cold or allergy symptoms, or anti-itch creams for the skin. Taking too much of this medicine could result in a fatal overdose.

Ask a doctor or pharmacist before using M-Dryl with any other medicines, especially those that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Inform your doctor about all your current medicines and any medicine you begin or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.