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Laxatives oral and topical powder for reconstitution (-)

Magnesium sulfate

Generic name: magnesium sulfate (epsom salt)

Brand names: Epsom Salt

Used for constipation
Last updated November 2, 2026 0 views
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What is magnesium sulfate?

Magnesium is a mineral that occurs naturally and is important for many body systems, especially the muscles and nerves. Magnesium sulfate also helps to increase water in the intestines.

Magnesium sulfate is used as a laxative to relieve occasional constipation.

Magnesium sulfate (Epsom salt) can be added to a bath as a soaking solution to help relieve minor sprains and bruises. Not all external uses of magnesium sulfate have been approved by the FDA. Epsom salt should not be used instead of medication prescribed by your doctor.

Magnesium sulfate may also be used for purposes not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I take magnesium sulfate?

Use exactly as directed on the label, or as prescribed by your doctor.

Never use a higher dose of magnesium sulfate than recommended on the package label, or as your doctor has directed. Using too much magnesium sulfate can cause serious, life-threatening side effects.

Magnesium sulfate may be used orally (by mouth) or as a soak. Follow your doctor's instructions or the directions on the package.

To take magnesium sulfate orally, dissolve one dose in 8 ounces of water. Stir this mixture and drink all of it right away. You may add a small amount of lemon juice to improve the taste of this mixture.

Magnesium sulfate taken orally should produce a bowel movement within 30 minutes to 6 hours.

Drink plenty of liquids while you are taking magnesium sulfate.

If you have rectal bleeding or if you do not have a bowel movement after using magnesium sulfate as a laxative, stop using the medication and call your doctor at once. These may be signs of a more serious condition.

To use magnesium sulfate as an epsom salt soak, dissolve in a large amount of water in a large bowl, a bucket, a foot tub, or a bath tub. Follow the directions on the product label about how much epsom salt to use per gallon of water.

Store at room temperature away from moisture and heat.

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Warnings

Never use a higher dose of magnesium sulfate than what is recommended on the package label or as directed by your doctor. Using too much magnesium sulfate can lead to serious, life-threatening side effects.

Do not use magnesium sulfate as a laxative without medical advice if you have: severe stomach pain, nausea, vomiting, a perforated bowel, a bowel obstruction, severe constipation, colitis, toxic megacolon, or a sudden change in bowel habits that has lasted 2 weeks or longer.

If you have rectal bleeding or if you do not have a bowel movement after using magnesium sulfate as a laxative, stop using the medication and call your doctor right away. These may be signs of a more serious condition.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

Do not use magnesium sulfate as a laxative without medical advice if you have:

  • severe stomach pain;
  • nausea or vomiting;
  • a perforated bowel;
  • a bowel obstruction or severe constipation;
  • colitis or toxic megacolon; or
  • a sudden change in bowel habits lasting 2 weeks or longer.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

  • diabetes;
  • kidney disease;
  • an eating disorder (anorexia or bulimia);
  • if you have already been using a laxative for longer than 1 week; or
  • if you are on a low-magnesium diet.

It is not known whether magnesium sulfate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether magnesium sulfate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

This section was rewritten for readability and reviewed for meaning.

Magnesium sulfate side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include diarrhea or upset stomach.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

What happens if I miss a dose?

Since magnesium sulfate is used as needed, you are unlikely to miss a dose.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of magnesium sulfate can be fatal.

Overdose symptoms may include nausea, vomiting, flushing (warmth, redness, or tingly feeling), feeling very hot, slow heart rate, extreme drowsiness, or fainting.

Taking magnesium sulfate by mouth can make it harder for your body to absorb other medications you take orally, especially antibiotics. Avoid taking other medicines within 2 hours before or after you take magnesium sulfate as a laxative.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect magnesium sulfate?

Other drugs may interact with magnesium sulfate, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform each of your health care providers about all medicines you are currently using and any medicine you begin or stop using.

This section was rewritten for readability and reviewed for meaning.

Common questions about magnesium sulfate

When is the best time to take magnesium, morning or night?
The best time of day to take magnesium depends on your health goals and individual needs. While timing can enhance specific benefits, maintaining a consistent routine is more important for stable magnesium levels in the body. Many studies show the full benefits of magnesium occur after long-term use. Continue reading
Should I take magnesium with or without food?
It is generally recommended to take magnesium with food to help lower the chances for an upset stomach and increase the absorption of the mineral into your body. If you take magnesium on an empty stomach, you increase the risk for common stomach side effects like diarrhea, nausea and abdominal cramping. Continue reading
Does magnesium help with restless leg syndrome (RLS)?
The evidence regarding magnesium's effectiveness for restless leg syndrome presents a complex picture. While some research suggests a beneficial effect, particularly for individuals with magnesium deficiency, other studies find no significant correlation between magnesium levels and RLS severity. Continue reading
What type of magnesium should I take?
The right type of magnesium depends on your health goals and personal needs. Different forms of magnesium have different benefits and levels of bioavailability. Continue reading
Does magnesium help with migraines and headaches?
The current evidence supports a role for magnesium in both the prevention and treatment of headache disorders, particularly migraines. Continue reading
Does magnesium help with weight loss?
While magnesium alone will not lead to significant weight loss, its ability to regulate blood sugar levels, reduce inflammation, improve gut health, boost metabolism, and enhance sleep quality makes it a valuable component of a holistic approach to weight management. Continue reading

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Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.