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Topical anti-infectives topical lotion (0.5%)

Malathion topical

Generic name: malathion topical

Brand names: Ovide

Used for head lice
Last updated November 2, 2026 0 views
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What is malathion topical?

Malathion topical is used to treat head lice.

Malathion topical may also be used for purposes not listed in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I use malathion topical?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Do not take by mouth. Malathion topical is for use only on your scalp.

Read and follow all Instructions for Use. Ask your doctor or pharmacist if you need help.

Wash your hands after applying the medication.

Do not wet your hair or scalp before applying malathion. Apply enough lotion to completely soak your scalp, including the back of your head and your neck.

Wash off the medicine right away if it causes severe scalp irritation. Reapply at a later time, and call your doctor if irritation occurs again.

Do not use a curling iron, hair dryer, or other heat styler on treated hair. Warn children to stay away from open flames, lighted cigarettes, and electric heat sources while the hair is wet.

Shampoo your hair after 8 to 12 hours. Rinse hair thoroughly. Use a nit comb to remove lice eggs from the hair. Rinse the nit comb often during use.

Do not allow a child to use malathion topical without help from an adult.

Wash all clothing, hats, bed clothes, bed linens, and towels in hot water and dry in high heat. Dry-clean any non-washable clothing. Hair brushes, combs, and hair accessories should be soaked in hot water.

Use this medicine again if you still see lice after 7 to 9 days.

Malathion lotion is flammable. Do not use near high heat or open flame. Do not smoke while applying this medicine. Avoid being near a lighted cigarette while your hair is still wet with malathion.

Store malathion at room temperature away from high heat, open flame, or electric heat sources.

This section was rewritten for readability and reviewed for meaning.

Warnings

Use only as directed. Inform your doctor if you are taking other medicines or have other medical conditions or allergies.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not use malathion topical if you are allergic to it.

Not approved for use by anyone younger than 6 years old. Malathion topical should not be used in newborns and infants.

Tell your doctor if you are pregnant or breastfeeding.

This section was rewritten for readability and reviewed for meaning.

Malathion topical side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor right away if you have severe stinging, burning, or irritation of your scalp that does not go away.

Less serious side effects may include mild stinging or irritation of your scalp.

This is not a complete list of side effects and others may happen. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

What happens if I miss a dose?

Malathion is used as a single dose and does not require taking it every day. Call your doctor if your symptoms do not improve after using this medicine.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical help or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed malathion topical.

Do not get this medicine in your eyes or on any skin other than your scalp. Rinse with water if this occurs. Call your doctor right away if you have severe stinging, itching, or irritation of the eyes or skin after rinsing.

To prevent spreading head lice, avoid head-to-head contact with others until your lice infection is completely gone. Do not share hair brushes, combs, hair accessories, hats, scarves, and pillows. Lice infections are highly contagious.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect malathion topical?

Medicine applied to the skin is not likely to be impacted by other medications you take, but many medications can interact. Inform your doctor about all your current medications, including prescription and over-the-counter medicines, vitamins, and herbal products.

This section was rewritten for readability and reviewed for meaning.

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.