Measles and rubella virus vaccine live (Intramuscular, Injection)

Measles and rubella virus vaccine live is a vaccine used to prevent infection from the measles and rubella viruses. It helps your body create its own protection (antibodies) against these viruses.

Measles (also called coughing measles, hard measles, morbilli, red measles, rubeola, and 10-day measles) is a highly contagious infection. Measles can lead to serious issues like pneumonia, ear infections, sinus problems, seizures, brain damage, and even death. The chances of serious complications and death are higher for adults and infants compared to children and teenagers.

Rubella (also known as German measles) is a serious infection that can cause miscarriages, stillbirths, or birth defects in unborn babies when pregnant women are infected.

Immunization against measles and rubella is recommended for everyone aged 12 months and older, but it is especially important for women who can become pregnant and people traveling outside the U.S.

If the measles and rubella vaccine is to be given to a child, the child must be at least 12 months old. This ensures that the measles vaccine works effectively. In younger children, antibodies from the mother might stop the vaccine from being effective.

This vaccine should only be given by or under the supervision of your doctor or another health care professional.

Do not become pregnant for 3 months after getting the measles and rubella vaccine without first checking with your doctor. There may be a chance that this vaccine can cause birth defects.

Tell your doctor that you have received this vaccine:

• If you are going to have a tuberculin skin test within 4 to 6 weeks after getting this vaccine. The results of the test may be affected by this vaccine.
• If you are going to receive blood products or immune globulins within 14 days of getting this vaccine.
• If you are going to get this vaccine within 3 to 11 months of receiving blood products or immune globulins.

In deciding to use a vaccine, you and your doctor will need to consider the risks of the vaccine compared to the benefits it may provide. For this vaccine, think about the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this vaccine or any other medications. Also, let your healthcare provider know if you have any other allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This vaccine is not recommended for infants younger than 12 months, unless there is a high risk of measles infection. It is important to wait until children are at least 12 months old because antibodies passed from mothers to infants before birth can affect how well the vaccine works. Additionally, there may be special reasons for vaccinating children between 6 months and 12 months of age.

Breast Feeding

Research suggests that this vaccine poses minimal risk to infants when used during breastfeeding.

Interactions with Medicines

Some medicines should not be used together at all, while others may be used together even if an interaction could occur. In those cases, your doctor may want to adjust the dose or take other precautions. It is especially important that your healthcare provider knows if you are taking any of the medicines listed below when receiving this vaccine. The following interactions have been identified based on their potential importance and are not necessarily a complete list.

It is not recommended to receive this vaccine with any of the following medicines. Your doctor may decide not to use this vaccine or change some of the other medicines you take.

• Alemtuzumab
• Bendamustine
• Bortezomib
• Bosutinib
• Cabazitaxel
• Capecitabine
• Carboplatin
• Carfilzomib
• Carmustine
• Chlorambucil
• Cisplatin
• Cladribine
• Clofarabine
• Cyclophosphamide
• Cytarabine
• Cytarabine Liposome
• Dacarbazine
• Dasatinib
• Daunorubicin
• Daunorubicin Citrate Liposome
• Daunorubicin Liposome
• Deflazacort
• Docetaxel
• Doxorubicin
• Epirubicin
• Etoposide
• Fludarabine
• Fluorouracil
• Gemcitabine
• Gemtuzumab Ozogamicin
• Hydroxyurea
• Idarubicin
• Ifosfamide
• Imatinib
• Interferon Alfa
• Irinotecan
• Irinotecan Liposome
• Lomustine
• Mechlorethamine
• Melphalan
• Mercaptopurine
• Methotrexate
• Mitomycin
• Mitoxantrone
• Nelarabine
• Nilotinib
• Ofatumumab
• Oxaliplatin
• Paclitaxel
• Paclitaxel Protein-Bound
• Pemetrexed
• Pentostatin
• Ponatinib
• Procarbazine
• Rituximab
• Temozolomide
• Teniposide
• Thiotepa
• Topotecan
• Tositumomab
• Vinblastine
• Vinorelbine

It is usually not recommended to receive this vaccine with any of the following medicines, but it may be necessary in some cases. If both medicines are prescribed together, your doctor may adjust the dose or how often you use one or both of the medicines.

• Adalimumab
• Anifrolumab-fnia
• Ansuvimab-zykl
• Antithymocyte Globulin Rabbit
• Atoltivimab
• Axicabtagene Ciloleucel
• Azathioprine
• Baricitinib
• Belatacept
• Betibeglogene Autotemcel
• Bimekizumab-bkzx
• Brexucabtagene Autoleucel
• Brodalumab
• Canakinumab
• Certolizumab Pegol
• Cyclosporine
• Deucravacitinib
• Dupilumab
• Efgartigimod Alfa-fcab
• Elivaldogene Autotemcel
• Emapalumab-lzsg
• Etanercept
• Etrasimod
• Everolimus
• Fingolimod
• Golimumab
• Guselkumab
• Hyaluronidase
• Immune Globulin
• Inebilizumab-cdon
• Infliximab
• Ixekizumab
• Leflunomide
• Leniolisib
• Meningococcal Vaccine
• Mirikizumab-mrkz
• Mycophenolic Acid
• Ocrelizumab
• Ozanimod
• Ponesimod
• Rilonacept
• Risankizumab-rzaa
• Ritlecitinib
• Rozanolixizumab-noli
• Sarilumab
• Satralizumab-mwge
• Secukinumab
• Siponimod
• Sirolimus
• Spesolimab-sbzo
• Tacrolimus
• Teplizumab-mzwv
• Teriflunomide
• Tildrakizumab-asmn
• Tocilizumab
• Tofacitinib
• Trabectedin
• Tralokinumab-ldrm
• Ublituximab-xiiy
• Upadacitinib
• Ustekinumab
• Valoctocogene Roxaparvovec-rvox
• Vamorolone
• Voclosporin

Receiving this vaccine with any of the following medicines may increase the risk of certain side effects, but using both may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Abatacept
• Cytomegalovirus Immune Globulin, Human
• Hepatitis B Immune Globulin
• Rabies Immune Globulin
• Respiratory Syncytial Virus Immune Globulin, Human
• Tetanus Immune Globulin
• Vaccinia Immune Globulin, Human
• Varicella-Zoster Immune Globulin

Interactions with Food/Tobacco/Alcohol

Some medicines should not be used close to mealtime or with certain types of food because interactions may happen. Using alcohol or tobacco with some medicines may also lead to interactions. Discuss with your healthcare provider about using your medicine with food, alcohol, or tobacco.

Other Medical Problems

Having other medical issues may affect the use of this vaccine. Be sure to tell your doctor if you have any other health problems, especially:

• Immune deficiency condition (or family history of)—This condition may increase the chances and severity of side effects from the vaccine and/or reduce the vaccine's effectiveness.

• Severe illness with fever—The symptoms might be confused with the possible side effects of the vaccine.

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do, they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Symptoms of allergic reaction

rare

• Difficulty in breathing or swallowing
• hives
• itching, especially of feet or hands
• reddening of skin, especially around ears
• swelling of eyes, face, or inside of nose
• unusual tiredness or weakness (sudden and severe)

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Fever over 103 °F (39.4 °C)

Less common

• Pain or tenderness of eyes

Rare

• Bruising or purple spots on skin
• confusion
• convulsions (seizures)
• double vision
• headache (severe or continuing)
• irritability
• pain, numbness, or tingling of hands, arms, legs, or feet
• stiff neck
• vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Burning or stinging at the place of injection
• fever between 100 and 103 °F (37.7 and 39.4 °C)
• skin rash
• swelling of glands in neck

Less common

• Aches or pain in joints
• headache (mild)
• itching, swelling, redness, tenderness, or hard lump at the place of injection
• nausea
• runny nose
• sore throat
• vague feeling of bodily discomfort

The above side effects (especially aches or pain in joints) are more likely to occur in adults, particularly women.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In Canada

• Eolarix

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For injection dosage form: For prevention of measles and rubella: Adults and children 12 months of age and older—One dose injected under the skin. Children up to 12 months of age—Use is not recommended.