Meni-D (Oral)

Meclizine is used to prevent and control nausea, vomiting, and dizziness that happen due to motion sickness. It is also used for vertigo (dizziness or lightheadedness) caused by ear issues.

Meclizine is an antihistamine. It works by blocking the signals to the brain that lead to nausea, vomiting, and dizziness.

This medicine is available only with a prescription from your doctor.

It is very important for your doctor to check your or your child's progress at regular visits to ensure that this medicine is working properly and to look for any unwanted effects.

This medicine may make some people feel drowsy or less alert than usual. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine will increase the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants include antihistamines or medicines for hay fever, other allergies, or colds, sedatives, tranquilizers, antidepressants, or sleeping medicines, prescription pain medicines or narcotics, medicines for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your medical doctor or dentist before taking any of the above while you or your child are using this medicine.

In deciding to use a medicine, you need to think about the risks of taking it compared to the benefits it may provide. This is a choice you will make with your doctor. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know about any other allergies you have, such as to foods, dyes, preservatives, or animals. For over-the-counter products, read the label or package ingredients carefully.

Pediatric

Studies have not been done to confirm how Antivert® tablets and chewable tablets affect children or how Antivert®/25 or Antivert®/50 tablets affect children younger than 12 years old. Safety and effectiveness have not been established.

Geriatric

Studies so far have not shown any specific problems in elderly patients that would limit the use of meclizine. However, older adults are more likely to have age-related issues with the liver, kidneys, or heart, which may require caution and a dose adjustment for those taking meclizine.

Breast Feeding

Research in women suggests that this medication poses minimal risk to babies when used during breastfeeding.

Interactions with Medicines

Some medicines should never be used together, while others can be used together even if there may be interactions. In these cases, your doctor may adjust the dose or take other precautions. It is very important that your healthcare provider knows if you are taking any of the medicines listed below. The following interactions are highlighted for their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Potassium Citrate
• Tranylcypromine

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in some cases. If both medicines are prescribed together, your doctor may adjust the dose or the frequency of one or both medicines.

• Alfentanil
• Alprazolam
• Amantadine
• Amifampridine
• Amobarbital
• Anileridine
• Benzhydrocodone
• Bromazepam
• Buprenorphine
• Bupropion
• Buspirone
• Butabarbital
• Butorphanol
• Calcium Oxybate
• Cannabidiol
• Cannabis
• Cetirizine
• Chloral Hydrate
• Chlordiazepoxide
• Chlorpromazine
• Clobazam
• Clonazepam
• Clorazepate
• Clozapine
• Codeine
• Daridorexant
• Dexmedetomidine
• Diazepam
• Difenoxin
• Dihydrocodeine
• Diphenhydramine
• Diphenoxylate
• Donepezil
• Doxylamine
• Esketamine
• Estazolam
• Eszopiclone
• Ethchlorvynol
• Ethylmorphine
• Fentanyl
• Flibanserin
• Flurazepam
• Fospropofol
• Gabapentin
• Gabapentin Enacarbil
• Glucagon
• Glycopyrrolate
• Glycopyrronium Tosylate
• Halazepam
• Hydrocodone
• Hydromorphone
• Hydroxyzine
• Ketamine
• Ketazolam
• Ketobemidone
• Lacosamide
• Lemborexant
• Levocetirizine
• Levorphanol
• Lofexidine
• Lorazepam
• Loxapine
• Magnesium Oxybate
• Meperidine
• Meprobamate
• Methacholine
• Methadone
• Methotrimeprazine
• Metoclopramide
• Midazolam
• Morphine
• Morphine Sulfate Liposome
• Nalbuphine
• Nicomorphine
• Nitrazepam
• Olanzapine
• Opium
• Opium Alkaloids
• Oxazepam
• Oxycodone
• Oxymorphone
• Papaveretum
• Paregoric
• Pentazocine
• Pentobarbital
• Periciazine
• Phenobarbital
• Piritramide
• Pitolisant
• Potassium Oxybate
• Prazepam
• Pregabalin
• Promethazine
• Propofol
• Propoxyphene
• Quazepam
• Quetiapine
• Ramelteon
• Remimazolam
• Revefenacin
• Ropeginterferon Alfa-2b-njft
• Scopolamine
• Secobarbital
• Secretin Human
• Sodium Oxybate
• Sufentanil
• Tapentadol
• Temazepam
• Thioridazine
• Tilidine
• Tiotropium
• Topiramate
• Tramadol
• Trazodone
• Triazolam
• Zaleplon
• Zolpidem
• Zopiclone
• Zuranolone

Interactions with Food/Tobacco/Alcohol

Some medicines should not be taken around the time of eating food or certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional how to take your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical issues may affect how this medicine works. Make sure to inform your doctor about any other medical problems you have, especially:

• Asthma or
• Enlarged prostate or
• Glaucoma—Use with caution. May worsen these conditions.

• Kidney disease or
• Liver disease—Use with caution. Effects may be stronger because the medicine is removed from the body more slowly.

Along with its necessary effects, a medicine may cause some unwanted effects. Not all of these side effects may happen, but if they do, they may need medical attention.

Check with your doctor right away if any of the following side effects occur:

Incidence not known

• Cough
• Difficulty swallowing
• Dizziness
• Drowsiness
• Fast heartbeat
• Hives, itching, skin rash
• Puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• Tightness in the chest
• Unusual tiredness or weakness
• Vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Your health care professional may also be able to tell you how to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Rare

• Blurred vision

Incidence not known

• Dry mouth
• Headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Antivert
• Antivert/25
• Antivert/50
• Dramamine II
• Meclicot
• Meni-D
• Motion Sickness Relief
• Simply Motion
• Travel Sickness

Available Dosage Forms:

• Tablet
• Tablet, Chewable

Therapeutic Class: Antiemetic

Pharmacologic Class: Antihistamine

Chemical Class: Piperazine (class)

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Chew or crush the chewable tablet completely before swallowing. Do not swallow it whole.

Swallow the non-chewable tablet whole. Do not crush, chew, or break it.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For oral dosage form (tablets): For nausea, vomiting, and dizziness caused by motion sickness: Adults—At first, 25 to 50 milligrams (mg) taken 1 hour before travel. You may take another dose once every 24 hours while traveling. Children 12 years of age and older—Use and dose must be determined by your doctor. Children younger than 12 years of age—Use is not recommended. For vertigo: Adults—25 to 100 milligrams (mg) per day, taken in divided doses. Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.