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Topical antifungals topical ointment (0.25%-15%)

Miconazole and zinc oxide topical

Generic name: miconazole and zinc oxide topical

Brand names: Rash Relief Antifungal, Daktozin, Vusion

Last updated November 2, 2026 0 views
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What is miconazole and zinc oxide topical?

Miconazole and zinc oxide topical (for the skin) is a combination antifungal medicine that treats infections caused by fungus.

The ointment form is used to treat diaper rash with a yeast infection (candidiasis) in children and babies who are at least 4 weeks old. Miconazole and zinc oxide topical ointment is only for diaper rash that has been diagnosed by a doctor.

The spray form is used to treat fungal infections of the skin, like athlete's foot (tinea pedis), jock itch (tinea cruris), or ringworm (tinea corporis). Miconazole and zinc oxide topical spray is for use by adults and children who are at least 2 years old.

Miconazole and zinc oxide topical should not be used to prevent diaper rash in either children or incontinent adults.

Miconazole and zinc oxide topical may also be used for purposes not listed in this medication guide.

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How should I use miconazole and zinc oxide topical?

Use exactly as directed on the label, or as prescribed by your doctor.

Your doctor may do lab tests to confirm you have the type of infection that this medicine can effectively treat.

Read and carefully follow any Instructions for Use that come with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Clean and dry the affected area before applying this medicine. You may use a mild soap.

Use the ointment for 1 week, each time you change a diaper. This medicine will not work without frequent diaper changes.

Change your child's diapers as soon as they become wet or soiled. Keep the diaper area clean and dry.

Do not use miconazole and zinc oxide topical to prevent diaper rash or you may increase your child's risk of an infection that is resistant to treatment. Miconazole and zinc oxide topical ointment is not for general diaper rash without a related yeast infection.

Allow the spray to dry completely before dressing. There is no need to rub in the medicine.

Use this medicine for the full prescribed length of time, even if your symptoms improve quickly. Skipping doses can increase your risk of an infection that is resistant to medication.

Do not share this medicine with another person, even if they have the same symptoms you have.

Stop using the medicine and call your doctor if symptoms do not improve, or if they get worse. Diaper rash should start to improve within 1 week of use. Jock itch should improve within 2 weeks, and athlete's foot should improve within 4 weeks. For best results, use this medicine as directed and follow all instructions for keeping the treatment area clean and dry.

Store at room temperature away from moisture and heat. Keep the tube or bottle tightly capped when not in use.

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Warnings

This medicine is not for preventing diaper rash.

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Before taking this medicine

You should not use miconazole and zinc oxide topical if you are allergic to miconazole, zinc, dimethicone, mineral oil, petroleum, or lanolin.

Do not use the ointment form of this medicine on a child younger than 4 weeks old.

Ask a doctor before using the topical spray on a child younger than 2 years old.

Tell your doctor if you have ever had:

  • a weak immune system caused by disease or by using certain medicines.

Ask a doctor before using this medicine if you are pregnant or breast-feeding.

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Miconazole and zinc oxide topical side effects

Get emergency medical help if you notice signs of an allergic reaction: hives; trouble breathing; swelling of your face, lips, tongue, or throat.

Miconazole and zinc oxide topical may cause serious side effects. Stop using miconazole and zinc oxide topical and call your doctor immediately if you experience:

  • severe discomfort, redness, or other irritation in the treated skin areas.

Less serious side effects may happen more often, and you might not experience any at all.

This is not a full list of side effects, and others may occur. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

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Miconazole and zinc oxide topical dosing information

Usual Pediatric Dose for Diaper Rash:

Diaper dermatitis complicated by documented candidiasis:4 weeks or older: Apply to affected area at each diaper change for 7 days.

What happens if I miss a dose?

Since miconazole and zinc oxide topical ointment is applied with each diaper change, it is unlikely that you will miss a dose.

If you are using the spray on a schedule, apply the medicine as soon as you can. If it is almost time for your next dose, skip the missed dose. Do not use two doses at the same time.

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What happens if I overdose?

An overdose of miconazole and zinc oxide topical is not expected to be dangerous. Seek emergency medical help or call the Poison Help line at 1-800-222-1222 if someone has accidentally swallowed the medication.

Avoid covering treated skin areas with tight-fitting, synthetic clothing (like nylon or polyester clothing, or plastic pants) that does not let air circulate to your skin. If you are treating your feet, wear clean cotton socks and sandals or shoes that allow for air circulation. Keep your feet as dry as possible.

Rinse with water if miconazole and zinc oxide topical gets in your eyes.

Avoid using scented or perfumed soaps or lotions to clean the diaper area.

Avoid getting this medication in the mouth or vagina.

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What other drugs will affect miconazole and zinc oxide topical?

Medicine applied to the skin is not likely to be influenced by other medications you take. However, many drugs can interact with one another. Inform all your healthcare providers about all the medicines you are using, including prescription and over-the-counter medicines, vitamins, and herbal products.

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Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
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Content is provided for education and is not medical advice. See our medical disclaimer.