Midol Extended Relief

Midol Extended Relief is a nonsteroidal anti-inflammatory drug (NSAID).

Midol Extended Relief is used to treat pain or swelling caused by conditions like arthritis, ankylosing spondylitis, tendinitis, bursitis, gout, or menstrual cramps.

The delayed-release or extended-release tablets are slower-acting types of naproxen that are meant only for treating long-term conditions like arthritis or ankylosing spondylitis. These types of naproxen will not work quickly enough to relieve sudden pain.

Midol Extended Relief may also be used for reasons not mentioned in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Use the lowest dose that effectively treats your condition.

Shake the oral suspension (liquid) before measuring a dose. Measure a dose with the provided measuring device (not a kitchen spoon).

Take Midol Extended Relief with food or milk if it makes your stomach upset.

Always follow the directions on the medicine label about giving this medicine to a child. Doses of Midol Extended Relief for children are based on their weight. Your child's dose may change if they gain or lose weight.

If you use Midol Extended Relief for a long time, you may need regular medical tests.

This medicine can affect the results of some medical tests. Inform any doctor who treats you that you are using Midol Extended Relief.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Midol Extended Relief can raise the risk of a serious heart attack or stroke. Do not use Midol Extended Relief right before or after heart bypass surgery (coronary artery bypass graft, or CABG). This medicine may also lead to bleeding in the stomach or intestines, which can be life-threatening.

Midol Extended Relief can increase your chances of having a fatal heart attack or stroke, even if you do not have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Midol Extended Relief may also lead to stomach or intestinal bleeding, which can be fatal. These issues can happen without warning while you are taking this medicine, especially in older adults.

You should not use Midol Extended Relief if you are allergic to it or if you have ever experienced an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

Ask a doctor before giving Midol Extended Relief to a child younger than 12 years old.

Ask a doctor or pharmacist if this medicine is safe for you if you have:

• heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke;
• a history of heart attack, stroke, or blood clot;
• stomach ulcers or bleeding;
• asthma;
• liver or kidney disease;
• fluid retention; or
• if you take aspirin to prevent heart attack or stroke.

If you are pregnant, you should not take Midol Extended Relief unless your doctor advises you to. Taking an NSAID during the last 20 weeks of pregnancy can lead to serious heart or kidney problems in the unborn baby and potential complications with your pregnancy.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risks.

Get emergency medical help if you notice signs of an allergic reaction, such as a runny or stuffy nose, wheezing or trouble breathing, hives, or swelling in your face or throat. Also seek immediate help for a severe skin reaction, which may include fever, sore throat, burning eyes, skin pain, or a red or purple skin rash with blistering and peeling.

Stop using Midol Extended Relief and get medical attention if you have a serious drug reaction that could affect multiple parts of your body. Symptoms may include a skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Get emergency medical help if you experience signs of a heart attack or stroke, such as chest pain that spreads to your jaw or shoulder, sudden numbness or weakness on one side of your body, slurred speech, leg swelling, or feeling short of breath.

Midol Extended Relief can cause serious side effects. Stop using it and call your doctor right away if you have:

• shortness of breath (even with mild exertion);
• swelling or rapid weight gain;
• any sign of a skin rash or blister, no matter how mild;
• signs of stomach bleeding, including bloody or tarry stools, coughing up blood, or vomit that looks like coffee grounds;
• liver problems, such as nausea, upper stomach pain, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes);
• kidney problems, which may include little or no urination, painful urination, or swelling in your feet or ankles; or
• low red blood cells (anemia), indicated by pale skin, unusual tiredness, feeling light-headed or short of breath, or cold hands and feet.

Common side effects of Midol Extended Relief may include:

• headache;
• indigestion, heartburn, or stomach pain; or
• flu symptoms;

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

Since Midol Extended Relief is taken as needed, you might not have a regular dosing schedule. If you miss a dose and it's almost time for your next one, just skip the missed dose. Do not take two doses at the same time.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222.

Do not drink alcohol. It may raise your risk of stomach bleeding.

Do not take aspirin or other NSAIDs unless your doctor instructs you to.

Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may have ingredients similar to Midol Extended Relief (like aspirin, ibuprofen, or ketoprofen).

Ask your doctor before using an antacid, and only use the type your doctor recommends. Some antacids can make it harder for your body to absorb Midol Extended Relief.

Ask your doctor before using Midol Extended Relief if you take an antidepressant. Using certain antidepressants with an NSAID may lead to easy bruising or bleeding.

Check with a doctor or pharmacist before using Midol Extended Relief with any other medications, especially:

• other NSAIDs or salicylates (diflunisal, salsalate);
• antacids and sucralfate;
• cholestyramine;
• cyclosporine;
• digoxin;
• lithium;
• methotrexate;
• pemetrexed;
• probenecid;
• warfarin (Coumadin, Jantoven) or similar blood thinners;
• a diuretic or "water pill"; or
• heart or blood pressure medication.

This list is not complete. Other drugs may affect Midol Extended Relief, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.