Midol PM

Acetaminophen helps relieve pain and reduce fever. Diphenhydramine is used to relieve allergy symptoms.

Midol PM is a combination medicine that helps with occasional sleeplessness related to minor aches and pains. Do not use Midol PM for sleeplessness that is not linked to pain or for sleep issues that happen frequently.

Midol PM also helps relieve minor aches and pains like headache, back pain, joint or muscle pain, tooth pain, or menstrual cramps.

Midol PM can also treat symptoms like runny nose, sneezing, itchy nose and throat, and pain or fever caused by allergies, the common cold, or the flu.

Midol PM may also be used for other reasons not mentioned in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. Midol PM is only for short-term use until your symptoms improve.

Do not take more of Midol PM than is recommended. An overdose of acetaminophen can harm your liver or cause death. Taking too much diphenhydramine can lead to serious heart issues, seizures, coma, or death.

Midol PM is not for use in anyone younger than 12 years old. Do not use the medicine to make a child sleepy. Death can occur from the misuse of antihistamines in very young children.

Do not use this medicine for more than 2 weeks to treat sleep problems, or more than 7 days to treat cold or allergy symptoms.

Call your doctor if you still have a fever after 3 days, or if you still have pain after 10 days (or 5 days if you are 12-17 years old). Also call your doctor if your symptoms worsen, or if you notice any redness or swelling.

If you need surgery or medical tests, inform the doctor in advance if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat.

Use Midol PM exactly as directed. Taking too much acetaminophen can harm your liver or cause death. Taking too much diphenhydramine can lead to serious heart issues, seizures, coma, or death.

Do not use this medicine to make a child sleepy. This medicine is not for anyone younger than 12 years old.

Ask a doctor or pharmacist before using any other medicine that may contain acetaminophen or diphenhydramine. Taking too much of either can lead to a fatal overdose.

Drinking alcohol may increase your risk of liver damage while taking acetaminophen.

Stop taking this medicine and call your doctor right away if you notice skin redness or a rash that spreads and causes blistering and peeling.

Ask a doctor before taking medicine that contains acetaminophen if you have ever had liver disease, or if you drink more than 3 alcoholic beverages each day.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

• liver disease;
• an enlarged prostate or urination problems;
• asthma, chronic obstructive pulmonary disease (COPD), emphysema, or other breathing disorder;
• glaucoma; or
• a condition for which you take warfarin (Coumadin, Jantoven).

Ask a doctor before using this medicine if you are pregnant or breastfeeding. Diphenhydramine may slow down breast milk production.

Get emergency medical help if you have signs of an allergic reaction: hives; trouble breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be life-threatening. This can happen even if you have taken acetaminophen before without any problems. Stop taking this medicine and call your doctor immediately if you notice skin redness or a rash that spreads and leads to blistering and peeling. If you experience this type of reaction, you should never take any medicine that contains acetaminophen again.

This medicine may cause serious side effects. Stop using it and call your doctor right away if you have:

• severe drowsiness;
• painful or difficult urination; or
• liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects of Midol PM may include:

• drowsiness;
• constipation;
• decreased urination;
• dry eyes, blurred vision; or
• dry mouth, nose, or throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Since Midol PM is taken as needed, you might not have a regular dosing schedule. If you miss a dose and it's nearly time for your next dose, just skip the missed dose. Do not take two doses at the same time.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal or cause liver damage.

Overdose symptoms may include loss of appetite, vomiting, weakness, confusion, ringing in your ears, upper stomach pain, dark urine, no urination, very dry eyes and mouth, yellowing of your skin or eyes, dilated pupils, fast heartbeats, tremor, agitation, hallucinations, or seizure.

Avoid driving or doing anything dangerous until you know how Midol PM will affect you. Your reactions might be affected.

Ask a doctor or pharmacist before using any other medicine that may contain acetaminophen or diphenhydramine. This includes medicines for pain, fever, swelling, cold/flu symptoms, or anti-itch medicine used on the skin. Using too much acetaminophen or diphenhydramine can lead to a fatal overdose.

Drinking alcohol may increase your risk of liver damage while taking acetaminophen.

Ask a doctor or pharmacist before using Midol PM with any other medicines, especially those that can cause drowsiness (such as opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures). Inform your doctor about all your current medicines and any medicine you begin or stop using. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.