Minocin (Intravenous)

Minocycline injection is used to treat bacterial infections in various parts of the body. It is also used to treat severe acne and intestinal amebiasis. Additionally, it is used for infections in patients who should not receive penicillin antibiotics.

Minocycline is part of a group of medicines called tetracycline antibiotics. It works by killing bacteria or stopping their growth. However, this medicine will not work for colds, flu, or other viral infections.

This medicine should only be given by or under the direct supervision of your doctor.

Your doctor will closely monitor your or your child's progress while you are receiving this medicine. This helps your doctor see if the medicine is effective and decide if treatment should continue. Blood and urine tests may be required to check for side effects.

Using this medicine during pregnancy can harm your unborn baby. It may also cause birth defects if the father is taking it when his partner becomes pregnant. If you become pregnant while using this medicine, inform your doctor immediately.

Birth control pills may not be as effective while you are using minocycline. To prevent pregnancy, use an additional form of birth control along with your pills. Other forms include condoms, a diaphragm, or contraceptive foam or jelly.

This medicine may change the color of your skin, nails, eyes, teeth, gums, or scars. Discuss any concerns with your doctor.

Contact your doctor immediately if you experience fever, rash, joint pain, or tiredness. These could be signs of an autoimmune syndrome where the body attacks itself.

Minocycline may make your skin more sensitive to sunlight. Even brief sun exposure may cause a rash, itching, redness, discoloration of the skin, or a severe sunburn. When you start using this medicine:

• Avoid direct sunlight, especially from 10:00 a.m. to 3:00 p.m., if possible.
• Wear protective clothing, including a hat, and sunglasses.
• Use a sunblock with a sun protection factor (SPF) of at least 15. Some patients, especially those with fair skin, may need a product with a higher SPF. If you have questions, consult your doctor.
• Use a sunblock lip product with an SPF of at least 15 to protect your lips.
• Do not use sun lamps or tanning beds or booths.

If you have a severe reaction to the sun, contact your doctor.

This medicine may cause dizziness or lightheadedness. Be cautious with driving, using machines, or any activities that could be dangerous until you know how this medicine affects you.

Minocycline may lead to diarrhea, which can be severe in some cases. This can happen 2 months or more after stopping the medicine. Do not take any medications for diarrhea without consulting your doctor first. Diarrhea medications may worsen the condition or prolong it. If you or your child have questions or if mild diarrhea persists or worsens, check with your doctor.

This medicine may increase pressure in your head, which could lead to permanent vision loss. Contact your doctor immediately if you or your child have severe headaches, blurred vision, or any changes in vision.

Inform your doctor right away if you or your child experience pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellowing of the eyes or skin. These could indicate a serious liver issue.

Before undergoing any medical tests, inform the medical doctor in charge that you or your child are using this medicine. Some test results may be influenced by this medication.

Do not take other medicines unless you have discussed it with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the benefits it will provide. This is a decision you and your doctor will make together. For this medicine, consider the following:

Allergies

Inform your doctor if you have ever had any unusual or allergic reactions to this medicine or any other medicines. Also, let your healthcare professional know if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Minocycline injection may cause permanent discoloration of teeth and slow down bone growth. This medicine should not be given to children younger than 8 years of age unless directed by the child's doctor.

Geriatric

Although appropriate studies on how age affects the effects of minocycline injection have not been done in older adults, there are no expected geriatric-specific problems that would limit the usefulness of minocycline injection in this group. However, older patients are more likely to have age-related kidney, liver, or heart issues, which may require caution and a dose adjustment for those receiving minocycline injection.

Breast Feeding

Studies suggest that this medication may change milk production or composition. If an alternative to this medication is not prescribed, you should watch the infant for side effects and ensure they are getting enough milk.

Interactions with Medicines

While some medicines should never be used together, in other cases, two different medicines might be used together even if an interaction could happen. In these instances, your doctor may want to adjust the dose, or other precautions may be necessary. It is very important that your healthcare professional knows if you are taking any of the medicines listed below when you receive this medicine. The following interactions are selected based on their potential significance and are not necessarily complete.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or may change some of the other medicines you take.

• Acitretin

Using this medicine with any of the following medicines is usually not recommended, but may be necessary in certain cases. If both medicines are prescribed together, your doctor may adjust the dose or how often you use one or both of the medicines.

• Amoxicillin
• Ampicillin
• Atazanavir
• Bacampicillin
• Bexarotene
• Cholera Vaccine, Live
• Cloxacillin
• Desogestrel
• Dicloxacillin
• Dienogest
• Digoxin
• Drospirenone
• Estradiol
• Ethinyl Estradiol
• Ethynodiol
• Etretinate
• Gestodene
• Isotretinoin
• Levoketoconazole
• Levonorgestrel
• Magnesium Sulfate
• Mestranol
• Methicillin
• Methotrexate
• Methoxyflurane
• Nafcillin
• Nomegestrol
• Norethindrone
• Norgestimate
• Norgestrel
• Oxacillin
• Palovarotene
• Penicillin G
• Penicillin G Benzathine
• Penicillin G Procaine
• Penicillin V
• Piperacillin
• Pivampicillin
• Porfimer
• Sultamicillin
• Temocillin
• Tretinoin

Using this medicine with any of the following medicines may increase the risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Aminolevulinic Acid
• Iron
• Vitamin A

Interactions with Food/Tobacco/Alcohol

Some medicines should not be used around the time of eating food or certain types of food due to possible interactions. Using alcohol or tobacco with certain medicines may also lead to interactions. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

Other medical issues may affect the use of this medicine. Make sure to inform your doctor if you have any other medical problems, especially:

• Diarrhea or
• Increased pressure in the head or
• Kidney disease or
• Liver disease—Use with caution. May worsen these conditions.

Along with its needed effects, Minocin (Intravenous) may cause some unwanted effects. Not all of these side effects may occur, but if they do, they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known

• Abdominal or stomach cramps or tenderness
• blistering, peeling, or loosening of the skin
• bloating
• bloody or cloudy urine
• blurred or double vision
• chills
• cough
• cracks in the skin
• dark urine
• diarrhea, watery and severe, which may also be bloody
• difficulty with swallowing
• dizziness
• eye pain
• fast heartbeat
• fever
• general tiredness and weakness
• greatly decreased frequency of urination or amount of urine
• hives, itching, or rash
• increased thirst
• joint or muscle pain
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• light-colored stools
• loss of heat from the body
• nausea or vomiting
• pain
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• red skin lesions, often with a purple center
• red, irritated eyes
• red, swollen skin
• scaly skin
• seizures
• severe headache
• severe stomach pain
• sore throat
• sores, ulcers, or white spots in the mouth or on the lips
• swelling of the feet or lower legs
• tightness in the chest
• trouble breathing
• unusual tiredness or weakness
• unusual weight loss
• upper right abdominal or stomach pain
• yellow eyes and skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to Minocin (Intravenous). Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Acid or sour stomach
• belching
• continuing ringing or buzzing or other unexplained noise in the ears
• difficulty with moving
• difficulty with swallowing
• discoloration of the nail, tooth, or gum
• hair loss or thinning of the hair
• hearing loss
• heartburn
• indigestion
• loss of appetite
• muscle pain or stiffness
• pain or redness at the injection site
• redness, swelling, or soreness of the tongue
• stomach discomfort or upset
• thick, white, or curd-like vaginal discharge
• weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

In the U.S.

• Minocin

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Antibiotic

Chemical Class: Tetracycline (class)

A nurse or other trained health professional will give you or your child this medicine in a hospital. This medicine is given through a needle placed in one of your veins.

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