On this page · 9 sections

Mucinex DM

Generic name: dextromethorphan and guaifenesin

Brand names: Alka-Seltzer Plus Maximum Strength, Children Giltuss Cough and Chest Congestion, Children's Delsym Cough+Chest Congest DM, Children's Robitussin Cough and Chest Congestion DM, Coricidin HBP Chest Congestion and Cough, Delsym Cough Plus Chest Congestion DM, Diabetic Tuss DM Maximum Strength, Fenesin DM IR, Geri-Tussin DM, Giltuss Cough and Chest Congestion, Giltuss Diabetic Cough and Cold, Guaiasorb DM, G-Zyncof, Kindermed Kids' Cough and Congestion, Max Tussin Cough + Chest Congestion DM, Max Tu

Used for common cold
Last updated November 2, 2026 0 views
Share

What is Mucinex DM?

Mucinex DM is a combination medicine used to treat cough and chest congestion caused by allergies, the common cold, or the flu.

Mucinex DM may also be used for reasons not mentioned in this medication guide.

This section was rewritten for readability and reviewed for meaning.

How should I take Mucinex DM?

Use this medicine exactly as it says on the label or as your doctor prescribed. Cold or cough medicine is meant for short-term use only.

Your dose might change if you switch to a different brand, strength, or form of this medicine. To avoid mistakes, use it exactly as directed on the label or as prescribed by your doctor.

Do not give this medicine to a child without checking with a doctor first. Follow all instructions when giving this medicine to a child. Do not use this medicine to make a child sleepy. Misusing this medicine can cause death in very young children.

Measure liquid medicine with the measuring device that comes with it (not a kitchen spoon).

You may need to shake the liquid before measuring a dose. Follow all instructions on the label.

Swallow the extended-release tablet whole; do not crush, chew, or break it.

Dissolve the effervescent tablets in at least 4 ounces of water. Stir and drink it right away. You can add more water to the glass, swirl it, and drink again.

Sprinkle the granules directly onto your tongue and swallow them right away.

Drink extra fluids to help loosen congestion and keep your throat moist while taking this medicine.

Contact your doctor if your symptoms do not get better after 7 days, or if you have a fever, rash, or headaches.

Follow the storage instructions that come with this medicine. Your pharmacist can give you more information on how to store it.

This section was rewritten for readability and reviewed for meaning.

Warnings

Do not use this medicine if you are currently using or have used an MAO inhibitor in the last 14 days. A serious drug interaction could happen. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

This section was rewritten for readability and reviewed for meaning.

Before taking this medicine

You should not take Mucinex DM if you are allergic to it.

Do not use Mucinex DM if you are currently using or have used an MAO inhibitor in the last 14 days, as a dangerous drug interaction could happen. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, and tranylcypromine.

Ask a doctor or pharmacist if this medicine is safe for you if you have:

  • a cough with mucus; or
  • asthma, emphysema, or chronic bronchitis.

This medicine may contain phenylalanine and could be harmful if you have phenylketonuria (PKU).

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

This section was rewritten for readability and reviewed for meaning.

Mucinex DM side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficulty breathing, swelling of your face, lips, tongue, or throat.

Mucinex DM may cause serious side effects. Stop using Mucinex DM and call your doctor right away if you have:

  • mood changes;
  • severe headache; or
  • severe dizziness or anxiety, feeling like you might pass out.

Common side effects of Mucinex DM may include:

  • dizziness, drowsiness;
  • sleep problems (insomnia);
  • diarrhea; or
  • feeling nervous, restless, anxious, or irritable.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You can report side effects to the FDA at 1-800-FDA-1088.

This section was rewritten for readability and reviewed for meaning.

What happens if I miss a dose?

Mucinex DM can be used as needed. If you are following a dosing schedule and miss a dose, just skip it. Do not take two doses at the same time.

This section was rewritten for readability and reviewed for meaning.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Avoid driving or doing anything that could be dangerous until you know how Mucinex DM will affect you. Your reactions could be impaired.

Ask a doctor or pharmacist before taking other cough or cold medicines that may have similar ingredients.

Drinking alcohol with this medicine can cause side effects.

This section was rewritten for readability and reviewed for meaning.

What other drugs will affect Mucinex DM?

Ask a doctor or pharmacist before using any other medicines that can make you sleepy, like opioid medication, sleep medicine, a muscle relaxer, or medicine for anxiety or seizures. Inform your doctor about all other medicines you take. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are included here.

This section was rewritten for readability and reviewed for meaning.

Common questions about Mucinex DM

Does Mucinex help you get pregnant?
Some research suggests that Mucinex may help increase fertility by keeping the cervical mucus thin around the time of ovulation, which ensures sperm can travel freely through the cervix and helps with sperm survival. An increase in fertility can help increase your chances of becoming pregnant. Women with hostile mucus as the only cause of their infertility are the ones most likely to benefit from guaifenesin treatment. You should always talk with your doctor before using Mucinex around the time of conception or while pregnant or breastfeeding. Continue reading
Does Mucinex help with Covid?
Mucinex does not prevent or cure COVID‑19, but it can help some people feel better by easing symptoms like chest congestion and cough. It should be used only for symptom relief and never as a substitute for COVID‑19–specific treatments, such as antivirals prescribed by your doctor. Continue reading
Can you take Mucinex or Mucinex DM while pregnant?
There is limited information on the use of Mucinex and Mucinex DM during pregnancy, but most experts advise avoiding these medications—especially in the first trimester—unless specifically directed by a healthcare provider. Continue reading

Related medicines

Before you take this medicine: the information on this page is general and may not cover your personal circumstances. Read the label supplied with your medicine and ask a pharmacist or doctor if you are unsure, especially if you are pregnant, breastfeeding, taking other medicines or managing a long-term condition.
General medicine information Consumer-friendly language

Content is provided for education and is not medical advice. See our medical disclaimer.