Mucinex Nightshift Cold and Flu

Acetaminophen is used to relieve pain and reduce fever. Dextromethorphan is used to suppress coughing. Triprolidine is an antihistamine.

Mucinex Nightshift Cold and Flu is a combination medicine that helps treat headache, fever, body aches, cough, sore throat, runny nose, sneezing, or sinus pressure caused by the flu or common cold.

Mucinex Nightshift Cold and Flu may also be used for other reasons not mentioned in this medication guide.

Use exactly as directed on the label, or as prescribed by your doctor. An acetaminophen overdose can damage your liver or cause death. Cold or cough medicine is only for short-term use until your symptoms clear up.

Always follow directions on the medicine label about giving cough or cold medicine to a child. Do not use the medicine only to make a child sleepy. Death can occur from the misuse of cough or cold medicines in very young children.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Call your doctor if you have a sore throat for more than 2 days, especially if you also have fever, headache, rash, nausea, or vomiting.

If you need surgery or medical tests, tell the surgeon or doctor if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

Do not use this medicine if you have used an MAO inhibitor in the past 14 days, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine.

An acetaminophen overdose can damage your liver or cause death. Call your doctor at once if you have stomach pain (upper right side), loss of appetite, tiredness, itching, dark urine, clay-colored stools, or yellowing of your skin or eyes.

Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.

Do not use this medicine only to make a child sleepy.

Do not use this medicine if you have taken an MAO inhibitor in the last 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not use this medicine if you are allergic to acetaminophen, dextromethorphan, or triprolidine.

Ask a doctor or pharmacist if this medicine is safe to use if you have:

• liver disease, cirrhosis, alcoholism, or more than 3 alcoholic beverages per day;
• glaucoma;
• a condition for which you take warfarin (Coumadin, Jantoven);
• an enlarged prostate or urination problems;
• breathing problems; or
• cough with mucus, or cough caused by smoking, asthma, or emphysema.

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could happen even if you have taken acetaminophen before without any issues. Stop taking this medicine and call your doctor immediately if you notice skin redness or a rash that spreads and causes blistering and peeling. If you have this type of reaction, you should never take any medicine that contains acetaminophen again.

This medicine may cause serious side effects. Stop using this medicine and call your doctor right away if you have:

• any new or worsening symptoms;
• nervousness, dizziness, or drowsiness;
• fever lasting more than 3 days;
• redness, swelling, or rash;
• a headache that does not go away; or
• pain, cough, or sinus congestion lasting more than 7 days.

Some side effects may be more common in older adults.

Common side effects of Mucinex Nightshift Cold and Flu may include:

• dizziness, drowsiness;
• dry mouth, nose, or throat;
• blurred vision;
• constipation;
• feeling restless or excited (especially in children); or
• sleep problems (insomnia).

This is not a complete list of side effects, and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Since Mucinex Nightshift Cold and Flu is used as needed, you may not have a set dosing schedule. If you miss a dose and it's nearly time for your next dose, just skip the missed dose. Do not take two doses at once.

Do not take more than 4 doses of this medicine in a 24-hour period.

Seek emergency medical help or call the Poison Help line at 1-800-222-1222. Taking too much acetaminophen can harm your liver or cause death.

Early signs of acetaminophen overdose include not wanting to eat, nausea, vomiting, sweating, or feeling weak. Later symptoms may include pain in the upper stomach, dark urine, and yellowing of your skin or eyes.

Do not drink alcohol. It may raise your risk of liver damage.

Do not drive or do anything dangerous until you know how this medicine affects you. Your reactions might be slower.

Ask a doctor or pharmacist before using any other medicine that may have acetaminophen (sometimes called APAP). Taking too much acetaminophen can lead to a fatal overdose.

Avoid using this medicine with other drugs that cause drowsiness or slow your breathing (such as opioid medicine, a muscle relaxer, or medicine for anxiety or seizures).

Ask a doctor or pharmacist before using any other medication, including prescription and over-the-counter medicines, vitamins, and herbal products.

Not all possible drug interactions are listed in this medication guide.