Mutamycin

Mutamycin is used along with other cancer drugs to treat stomach and pancreatic cancer.

Mutamycin may also be used for reasons not mentioned in this medication guide.

Mutamycin can harm red blood cells, which may lead to irreversible kidney failure. Contact your doctor immediately if you notice unusual bruising or bleeding, pale skin, confusion, tiredness, irritability, stomach pain, bloody diarrhea, red or pink urine, swelling, rapid weight gain, or if you are urinating very little or not at all.

Mutamycin can also weaken (suppress) your immune system, making it easier for you to get an infection. Call your doctor if you experience signs of infection, such as fever, weakness, cold or flu symptoms, skin sores, or frequent or recurring illnesses.

You should not receive treatment with Mutamycin if you are allergic to it, or if you have:

• low levels of platelets in your blood;
• bone marrow suppression; or
• active bleeding or any risk of bleeding.

Inform your doctor if you have ever had:

• kidney disease;
• heart disease; or
• asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or another breathing disorder.

Mutamycin may harm an unborn baby. Use effective birth control to prevent pregnancy, and inform your doctor if you become pregnant.

You should not breastfeed while using Mutamycin.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Mutamycin can damage red blood cells, which may cause irreversible kidney failure. Tell your doctor right away if you have unusual bruising or bleeding, pale skin, confusion, tiredness or irritability, stomach pain, bloody diarrhea, red or pink urine, swelling, rapid weight gain, and little or no urinating.

Mutamycin may cause serious side effects. Call your doctor at once if you have:

• signs of infection (fever, weakness, cold or flu symptoms, skin sores, frequent or recurring illness);
• wheezing, chest tightness, new or worsening cough, trouble breathing;
• blisters or ulcers in your mouth, red or swollen gums, trouble swallowing; or
• pain, burning, redness, swelling, irritation, or skin changes where the injection was given.

Common side effects of Mutamycin may include:

• fever or other signs of infection;
• nausea, vomiting, diarrhea, loss of appetite;
• mouth sores;
• drowsiness, headache;
• blurred vision; or
• temporary hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Mutamycin is given as an infusion into a vein. A healthcare provider will give you Mutamycin.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Mutamycin is injected.

Some people receiving Mutamycin have developed ulcers on the skin where an injection was given, or on other areas of body. Skin changes may occur several weeks or months after a this medicine injection. Call your doctor if you notice any redness, sores, oozing, or other skin changes during or after your treatment with this medicine.

Mutamycin affects your immune system. You may get infections more easily. You will need frequent medical tests, and your next dose may be delayed based on the results.

Mutamycin can have long lasting effects on your body. You may also need medical tests for a short time after your last dose.

Call your doctor for instructions if you miss an appointment for your Mutamycin.

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

Avoid being around people who are sick or have infections. Tell your doctor right away if you notice any signs of infection.

Avoid activities that could increase your risk of bleeding or injury. Be extra careful to prevent bleeding while shaving or brushing your teeth.

Other drugs may affect Mutamycin, including prescription and over-the-counter medicines, vitamins, and herbal products. Inform your doctor about all your current medicines and any medicine you begin or discontinue.